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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNRHR
All Species:
19.09
Human Site:
S74
Identified Species:
42
UniProt:
P30968
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30968
NP_000397.1
328
37731
S74
K
E
K
G
K
K
L
S
R
M
K
L
L
L
K
Chimpanzee
Pan troglodytes
XP_526608
328
37738
S74
K
E
K
G
K
K
L
S
R
M
K
L
L
L
K
Rhesus Macaque
Macaca mulatta
Q95JG1
379
41441
R76
Q
L
R
P
S
P
V
R
T
L
F
A
H
L
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q01776
327
37665
S74
R
K
K
G
K
K
L
S
R
M
K
V
L
L
K
Rat
Rattus norvegicus
P30969
327
37729
S74
R
K
K
G
K
K
L
S
R
M
K
V
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001116830
332
37290
P78
R
G
K
K
K
R
L
P
R
M
K
V
L
L
K
Chicken
Gallus gallus
NP_001012627
419
45457
S100
G
R
R
G
G
G
R
S
H
I
R
V
L
L
R
Frog
Xenopus laevis
NP_001079176
368
41711
C107
W
Y
A
G
E
L
S
C
K
V
L
N
F
G
K
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
L76
A
D
V
Y
I
G
N
L
A
L
A
D
L
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001035354
349
40615
H74
R
V
S
K
S
R
I
H
I
M
L
M
H
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001116990
440
49788
S102
W
R
E
R
R
R
K
S
R
I
N
L
L
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
35.6
N.A.
N.A.
89.3
87.5
N.A.
70.4
32.9
38.8
21.1
N.A.
N.A.
30
N.A.
26.1
Protein Similarity:
100
100
50.4
N.A.
N.A.
94.5
93.5
N.A.
81.9
49.1
56.2
39.8
N.A.
N.A.
51.8
N.A.
43.6
P-Site Identity:
100
100
6.6
N.A.
N.A.
80
80
N.A.
60
26.6
13.3
6.6
N.A.
N.A.
13.3
N.A.
26.6
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
80
60
33.3
20
N.A.
N.A.
40
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
10
0
10
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
19
10
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% F
% Gly:
10
10
0
55
10
19
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
10
0
0
0
19
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
10
19
0
0
0
10
0
% I
% Lys:
19
19
46
19
46
37
10
0
10
0
46
0
0
0
55
% K
% Leu:
0
10
0
0
0
10
46
10
0
19
19
28
73
73
0
% L
% Met:
0
0
0
0
0
0
0
0
0
55
0
10
0
0
10
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
37
19
19
10
10
28
10
10
55
0
10
0
0
0
10
% R
% Ser:
0
0
10
0
19
0
10
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
10
10
0
0
0
10
0
0
10
0
37
0
0
0
% V
% Trp:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _