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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNRHR All Species: 8.48
Human Site: T190 Identified Species: 18.67
UniProt: P30968 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30968 NP_000397.1 328 37731 T190 L A D S S G Q T K V F S Q C V
Chimpanzee Pan troglodytes XP_526608 328 37738 T190 L A D S S G Q T K V F S Q C V
Rhesus Macaque Macaca mulatta Q95JG1 379 41441 G192 F T Q C V T K G S F K A R W Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q01776 327 37665 T190 L A D G S G P T V F S Q C V T
Rat Rattus norvegicus P30969 327 37729 A190 L A D G S G P A V F S Q C V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus NP_001116830 332 37290 M194 I T D S S G K M D T F S Q C V
Chicken Gallus gallus NP_001012627 419 45457 T216 L H A P H N F T Q C T T H G S
Frog Xenopus laevis NP_001079176 368 41711 L223 I V C Y T R I L W E I G K Q M
Zebra Danio Brachydanio rerio A0T2N3 359 40129 L192 S C A M D F N L V V S Q P G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera NP_001035354 349 40615 V190 V T W Y S Q C V T F N A F P T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001116990 440 49788 T218 P P E D P S F T Q C V D Y N F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 35.6 N.A. N.A. 89.3 87.5 N.A. 70.4 32.9 38.8 21.1 N.A. N.A. 30 N.A. 26.1
Protein Similarity: 100 100 50.4 N.A. N.A. 94.5 93.5 N.A. 81.9 49.1 56.2 39.8 N.A. N.A. 51.8 N.A. 43.6
P-Site Identity: 100 100 0 N.A. N.A. 40 33.3 N.A. 60 13.3 0 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 20 N.A. N.A. 40 33.3 N.A. 73.3 26.6 26.6 6.6 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 37 19 0 0 0 0 10 0 0 0 19 0 0 0 % A
% Cys: 0 10 10 10 0 0 10 0 0 19 0 0 19 28 0 % C
% Asp: 0 0 46 10 10 0 0 0 10 0 0 10 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 10 19 0 0 37 28 0 10 0 10 % F
% Gly: 0 0 0 19 0 46 0 10 0 0 0 10 0 19 0 % G
% His: 0 10 0 0 10 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 19 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 19 0 19 0 10 0 10 0 0 % K
% Leu: 46 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 10 10 0 0 0 10 0 0 10 0 % N
% Pro: 10 10 0 10 10 0 19 0 0 0 0 0 10 10 0 % P
% Gln: 0 0 10 0 0 10 19 0 19 0 0 28 28 10 19 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % R
% Ser: 10 0 0 28 55 10 0 0 10 0 28 28 0 0 10 % S
% Thr: 0 28 0 0 10 10 0 46 10 10 10 10 0 0 28 % T
% Val: 10 10 0 0 10 0 0 10 28 28 10 0 0 19 28 % V
% Trp: 0 0 10 0 0 0 0 0 10 0 0 0 0 10 0 % W
% Tyr: 0 0 0 19 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _