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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALCR All Species: 33.03
Human Site: T346 Identified Species: 72.67
UniProt: P30988 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30988 NP_001733.1 490 57303 T346 L V T K M R E T H E A E S H M
Chimpanzee Pan troglodytes XP_001167949 508 59345 T364 L V T K M R E T H E A E S H M
Rhesus Macaque Macaca mulatta Q76LL8 415 47765 F286 V L L I N F I F L F N I V R I
Dog Lupus familis XP_539423 553 64271 T408 L V S K M R E T Q E A E S H M
Cat Felis silvestris
Mouse Mus musculus Q60755 515 60148 T367 L V T K M R Q T H E A E S Y M
Rat Rattus norvegicus P32214 516 60274 T367 L V T K M R Q T H E A E A Y M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90812 420 48581 F291 V L L I N F I F L F N I V R I
Frog Xenopus laevis Q7ZXS8 476 54963 T338 L I T K L K V T H Q A E S N L
Zebra Danio Brachydanio rerio Q68EK2 470 54084 T331 L I T K L K V T H Q A K S S L
Tiger Blowfish Takifugu rubipres NP_001098689 794 91578 T654 L V T K L R D T H R A E S N M
Fruit Fly Dros. melanogaster Q9W4Y2 669 74467 S436 L V M K L R Q S Q A S D I E Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 27.7 77.5 N.A. 66.4 69.1 N.A. N.A. 29.7 53 50.2 35.6 24 N.A. N.A. N.A.
Protein Similarity: 100 96.4 46.9 81 N.A. 80 80.6 N.A. N.A. 48.1 67.5 67.3 46.6 39 N.A. N.A. N.A.
P-Site Identity: 100 100 0 86.6 N.A. 86.6 80 N.A. N.A. 0 53.3 46.6 73.3 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 93.3 N.A. 100 100 N.A. N.A. 20 93.3 86.6 93.3 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 73 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 28 0 0 46 0 64 0 10 0 % E
% Phe: 0 0 0 0 0 19 0 19 0 19 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 64 0 0 0 0 28 0 % H
% Ile: 0 19 0 19 0 0 19 0 0 0 0 19 10 0 19 % I
% Lys: 0 0 0 82 0 19 0 0 0 0 0 10 0 0 0 % K
% Leu: 82 19 19 0 37 0 0 0 19 0 0 0 0 0 19 % L
% Met: 0 0 10 0 46 0 0 0 0 0 0 0 0 0 55 % M
% Asn: 0 0 0 0 19 0 0 0 0 0 19 0 0 19 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 28 0 19 19 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 64 0 0 0 10 0 0 0 19 0 % R
% Ser: 0 0 10 0 0 0 0 10 0 0 10 0 64 10 0 % S
% Thr: 0 0 64 0 0 0 0 73 0 0 0 0 0 0 0 % T
% Val: 19 64 0 0 0 0 19 0 0 0 0 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _