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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NTSR1 All Species: 22.42
Human Site: S404 Identified Species: 44.85
UniProt: P30989 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30989 NP_002522.2 418 46259 S404 R K A D S V S S N H T L S S N
Chimpanzee Pan troglodytes XP_514769 418 46021 S404 R K A N S V S S N H T L S S N
Rhesus Macaque Macaca mulatta XP_001087416 336 36637 R323 W L P Y H V R R L M F C Y I S
Dog Lupus familis XP_543088 421 46451 S407 R K T N S V S S N H T F S S N
Cat Felis silvestris
Mouse Mus musculus O88319 424 47198 S410 R K P N S M S S N H A F S T S
Rat Rattus norvegicus P20789 424 47036 S410 R K P N S M S S N H A F S T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506365 416 46666 S402 G K S N S I S S N H T F S S N
Chicken Gallus gallus O93603 395 44679 S381 V T N T Y L S S A K T S I G D
Frog Xenopus laevis P70031 453 51139 A437 E D I A A T G A S L S K F S Y
Zebra Danio Brachydanio rerio A0T2N3 359 40129 S346 A S P A S S L S S Q K T E A Q
Tiger Blowfish Takifugu rubipres NP_001098705 417 46824 E401 A S L S K M E E S K T T L Q T
Fruit Fly Dros. melanogaster Q8ITC7 477 53986 R399 R E S S A Y D R V H S V H V R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.7 79.1 85.2 N.A. 84.6 83.7 N.A. 73.2 22.9 22.7 25.3 32 25.5 N.A. N.A. N.A.
Protein Similarity: 100 91.8 79.1 90.2 N.A. 89.6 89.1 N.A. 84.6 44.5 42.5 43.7 48.5 45.7 N.A. N.A. N.A.
P-Site Identity: 100 93.3 6.6 80 N.A. 53.3 53.3 N.A. 66.6 20 6.6 13.3 6.6 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 86.6 N.A. 80 80 N.A. 86.6 33.3 33.3 26.6 20 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 17 17 17 0 0 9 9 0 17 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 9 0 9 0 0 9 0 0 0 0 0 0 0 9 % D
% Glu: 9 9 0 0 0 0 9 9 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 34 9 0 0 % F
% Gly: 9 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 9 0 0 0 0 59 0 0 9 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 0 0 9 9 0 % I
% Lys: 0 50 0 0 9 0 0 0 0 17 9 9 0 0 0 % K
% Leu: 0 9 9 0 0 9 9 0 9 9 0 17 9 0 0 % L
% Met: 0 0 0 0 0 25 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 9 42 0 0 0 0 50 0 0 0 0 0 34 % N
% Pro: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 9 % Q
% Arg: 50 0 0 0 0 0 9 17 0 0 0 0 0 0 9 % R
% Ser: 0 17 17 17 59 9 59 67 25 0 17 9 50 42 25 % S
% Thr: 0 9 9 9 0 9 0 0 0 0 50 17 0 17 9 % T
% Val: 9 0 0 0 0 34 0 0 9 0 0 9 0 9 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 9 0 0 0 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _