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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NTS All Species: 24.55
Human Site: T43 Identified Species: 67.5
UniProt: P30990 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30990 NP_006174.1 170 19795 T43 D F L T N M H T S K I S K A H
Chimpanzee Pan troglodytes XP_001165130 170 19867 T43 D F L T N M H T S K M S K A H
Rhesus Macaque Macaca mulatta XP_001090068 170 19831 T43 D L L T S M H T S K I S K A H
Dog Lupus familis XP_854478 170 19844 T43 D L L T N M H T S K I S K A S
Cat Felis silvestris
Mouse Mus musculus Q9D3P9 169 19589 T42 D L L T N M H T S K I S K A S
Rat Rattus norvegicus P20068 169 19545 A42 D L L T N M H A S K V S K G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511940 187 21447 Q61 I Q D S S I N Q S K I S K A R
Chicken Gallus gallus XP_416126 164 18982 T39 D L L T N M Y T S K M N R A K
Frog Xenopus laevis NP_001086150 166 19511 S42 D V L S N I Y S S K V N K A R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 96.4 90 N.A. 81.1 77.6 N.A. 56.1 64.7 58.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 98.2 91.7 N.A. 90 88.2 N.A. 71.6 80 74.7 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 86.6 86.6 N.A. 86.6 66.6 N.A. 40 60 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 73.3 N.A. 66.6 86.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 0 0 0 0 89 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 89 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % G
% His: 0 0 0 0 0 0 67 0 0 0 0 0 0 0 34 % H
% Ile: 12 0 0 0 0 23 0 0 0 0 56 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 100 0 0 89 0 12 % K
% Leu: 0 56 89 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 78 0 0 0 0 23 0 0 0 0 % M
% Asn: 0 0 0 0 78 0 12 0 0 0 0 23 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 23 % R
% Ser: 0 0 0 23 23 0 0 12 100 0 0 78 0 0 34 % S
% Thr: 0 0 0 78 0 0 0 67 0 0 0 0 0 0 0 % T
% Val: 0 12 0 0 0 0 0 0 0 0 23 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _