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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDI1
All Species:
36.06
Human Site:
Y421
Identified Species:
79.33
UniProt:
P31150
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31150
NP_001484.1
447
50583
Y421
C
N
D
I
K
D
I
Y
K
R
M
A
G
T
A
Chimpanzee
Pan troglodytes
XP_507638
754
84691
Y730
C
D
D
I
K
N
I
Y
K
R
M
T
G
S
E
Rhesus Macaque
Macaca mulatta
XP_001092845
425
48256
Y399
C
N
D
I
K
D
I
Y
K
R
M
A
G
M
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P50396
447
50503
Y421
C
N
D
I
K
D
I
Y
K
R
M
A
G
S
A
Rat
Rattus norvegicus
P50398
447
50518
Y421
C
N
D
I
K
D
I
Y
K
R
M
A
G
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516117
557
61407
Y530
C
D
D
I
K
D
I
Y
K
R
M
M
G
S
E
Chicken
Gallus gallus
NP_990335
448
50664
Y421
C
D
D
I
K
D
I
Y
K
R
M
M
G
S
E
Frog
Xenopus laevis
NP_001087753
447
50761
Y421
C
N
D
I
K
D
I
Y
K
R
M
T
G
T
D
Zebra Danio
Brachydanio rerio
NP_001018444
447
50457
Y421
C
N
D
I
K
D
I
Y
K
R
M
T
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
F455
I
A
N
A
R
D
I
F
G
K
M
F
P
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
Y432
T
D
D
V
K
D
I
Y
F
R
V
T
G
H
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.1
94.6
N.A.
N.A.
97.9
98.6
N.A.
68.4
87.2
92.3
91.9
N.A.
23.4
N.A.
N.A.
N.A.
Protein Similarity:
100
55.7
94.8
N.A.
N.A.
99.3
99.5
N.A.
74.6
94.4
96.1
95.9
N.A.
44.6
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
93.3
N.A.
N.A.
93.3
93.3
N.A.
73.3
73.3
86.6
80
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
93.3
N.A.
N.A.
100
100
N.A.
86.6
86.6
86.6
86.6
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
76.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
0
0
37
0
0
46
% A
% Cys:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
37
91
0
0
91
0
0
0
0
0
0
0
10
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
28
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
91
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
82
0
0
100
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
91
0
0
0
82
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
91
19
0
10
0
% M
% Asn:
0
55
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
91
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
37
0
19
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _