KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK4
All Species:
12.42
Human Site:
S376
Identified Species:
30.37
UniProt:
P31152
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31152
NP_002738.2
587
65922
S376
P
D
R
C
Q
D
A
S
E
V
Q
R
D
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094390
587
65900
S376
P
D
R
C
Q
D
A
S
E
V
Q
R
D
P
R
Dog
Lupus familis
XP_548811
584
65457
V374
R
G
Q
D
A
S
E
V
Q
R
D
P
R
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5G0
583
65556
S372
P
D
R
C
Q
D
A
S
E
V
Q
R
D
P
R
Rat
Rattus norvegicus
P27704
720
82256
E392
L
S
D
V
T
D
E
E
E
V
Q
V
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508507
579
65970
S372
H
D
R
Y
Q
A
T
S
E
V
Q
R
D
P
R
Chicken
Gallus gallus
Q5F3W3
721
82729
E392
L
S
D
V
T
D
E
E
E
V
Q
V
D
P
R
Frog
Xenopus laevis
P26696
361
41238
C164
N
L
L
L
N
T
T
C
D
L
K
I
C
D
F
Zebra Danio
Brachydanio rerio
NP_998638
674
75893
D390
E
D
E
E
V
Q
R
D
P
R
A
S
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792156
763
86571
K471
E
A
K
W
E
D
F
K
E
M
M
S
M
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
92.8
N.A.
93.5
48
N.A.
83.9
48.6
28.2
53.8
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
N.A.
99.3
94.7
N.A.
95.5
60.9
N.A.
90.1
61.8
42.4
65.7
N.A.
N.A.
N.A.
N.A.
48.8
P-Site Identity:
100
N.A.
100
0
N.A.
100
46.6
N.A.
73.3
46.6
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
46.6
N.A.
73.3
46.6
20
6.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
30
0
0
0
10
0
0
20
0
% A
% Cys:
0
0
0
30
0
0
0
10
0
0
0
0
10
0
0
% C
% Asp:
0
50
20
10
0
60
0
10
10
0
10
0
60
20
0
% D
% Glu:
20
0
10
10
10
0
30
20
70
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
20
10
10
10
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
10
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
30
0
0
0
0
0
0
0
10
0
0
10
0
60
10
% P
% Gln:
0
0
10
0
40
10
0
0
10
0
60
0
0
0
0
% Q
% Arg:
10
0
40
0
0
0
10
0
0
20
0
40
10
0
60
% R
% Ser:
0
20
0
0
0
10
0
40
0
0
0
20
10
0
10
% S
% Thr:
0
0
0
0
20
10
20
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
20
10
0
0
10
0
60
0
20
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _