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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAT2A
All Species:
62.73
Human Site:
S206
Identified Species:
86.25
UniProt:
P31153
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31153
NP_005902.1
395
43661
S206
R
V
H
T
I
V
I
S
V
Q
H
D
E
E
V
Chimpanzee
Pan troglodytes
XP_515585
413
45605
S206
R
V
H
T
I
V
I
S
V
Q
H
D
E
E
V
Rhesus Macaque
Macaca mulatta
XP_001083990
438
48324
S249
R
V
H
T
I
V
I
S
V
Q
H
D
E
E
V
Dog
Lupus familis
XP_532980
395
43656
S206
R
V
H
T
I
V
I
S
V
Q
H
D
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3THS6
395
43670
S206
R
V
H
T
I
V
I
S
V
Q
H
D
E
E
V
Rat
Rattus norvegicus
P18298
395
43697
S206
R
V
H
T
I
V
I
S
V
Q
H
D
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508946
392
42919
S203
R
V
H
T
I
V
I
S
V
Q
H
D
E
D
V
Chicken
Gallus gallus
XP_421512
396
43734
S207
R
V
H
T
I
V
I
S
V
Q
H
D
E
T
V
Frog
Xenopus laevis
NP_001080175
396
43767
S207
R
V
H
T
I
V
V
S
V
Q
H
D
E
H
I
Zebra Danio
Brachydanio rerio
NP_001014318
363
40041
I204
L
P
I
R
V
H
T
I
V
I
S
V
Q
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40320
408
44678
S217
R
V
H
T
I
V
V
S
M
Q
H
S
E
K
I
Honey Bee
Apis mellifera
XP_623669
404
44652
S214
R
V
H
T
V
V
V
S
L
Q
H
S
E
K
I
Nematode Worm
Caenorhab. elegans
P50305
404
44016
S194
R
V
H
T
V
V
I
S
T
Q
H
S
P
D
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
A9PDZ7
393
42904
S194
R
V
H
T
V
L
I
S
T
Q
H
D
E
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUT2
393
42777
S194
R
V
H
T
V
L
I
S
T
Q
H
D
E
T
V
Baker's Yeast
Sacchar. cerevisiae
P10659
382
41800
S193
R
I
D
T
V
V
V
S
A
Q
H
A
D
E
I
Red Bread Mold
Neurospora crassa
P48466
395
42967
S205
R
V
D
T
V
V
V
S
A
Q
H
A
P
E
I
Conservation
Percent
Protein Identity:
100
93.9
84.9
99.7
N.A.
99.4
98.4
N.A.
77.9
84
91.1
82.2
N.A.
71.3
71.7
70.5
N.A.
Protein Similarity:
100
94.1
86.3
100
N.A.
100
99.7
N.A.
82
92.4
97.4
88.3
N.A.
85.5
85.4
81.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
80
6.6
N.A.
66.6
60
60
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
20
N.A.
93.3
93.3
80
N.A.
Percent
Protein Identity:
64.8
N.A.
N.A.
64.3
66
68.8
Protein Similarity:
76.2
N.A.
N.A.
78.2
81.5
83
P-Site Identity:
73.3
N.A.
N.A.
73.3
46.6
53.3
P-Site Similarity:
86.6
N.A.
N.A.
86.6
80
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
65
6
12
6
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
77
48
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
83
0
0
6
0
0
0
0
95
0
0
12
0
% H
% Ile:
0
6
6
0
59
0
65
6
0
6
0
0
0
0
36
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
6
0
0
0
0
12
0
0
6
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
6
0
0
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
95
0
0
6
0
0
% Q
% Arg:
95
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
95
0
0
6
18
0
0
0
% S
% Thr:
0
0
0
95
0
0
6
0
18
0
0
0
0
18
0
% T
% Val:
0
89
0
0
42
83
30
0
59
0
0
6
0
0
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _