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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAT2A
All Species:
46.97
Human Site:
S22
Identified Species:
64.58
UniProt:
P31153
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31153
NP_005902.1
395
43661
S22
E
G
T
F
L
F
T
S
E
S
V
G
E
G
H
Chimpanzee
Pan troglodytes
XP_515585
413
45605
S22
E
G
T
F
L
F
T
S
E
S
V
G
E
G
H
Rhesus Macaque
Macaca mulatta
XP_001083990
438
48324
D65
G
G
G
P
M
P
R
D
V
V
W
L
H
C
L
Dog
Lupus familis
XP_532980
395
43656
S22
E
G
T
F
L
F
T
S
E
S
V
G
E
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3THS6
395
43670
S22
E
G
T
F
L
F
T
S
E
S
V
G
E
G
H
Rat
Rattus norvegicus
P18298
395
43697
S22
E
G
T
F
L
F
T
S
E
S
V
G
E
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508946
392
42919
S15
D
N
Q
Q
T
V
H
S
E
V
L
G
Q
L
G
Chicken
Gallus gallus
XP_421512
396
43734
S23
E
G
A
F
M
F
T
S
E
S
V
G
E
G
H
Frog
Xenopus laevis
NP_001080175
396
43767
S23
E
G
S
F
L
F
T
S
E
S
V
G
E
G
H
Zebra Danio
Brachydanio rerio
NP_001014318
363
40041
S23
E
D
C
F
L
F
T
S
E
S
V
G
E
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40320
408
44678
S33
G
A
T
F
L
F
T
S
E
S
V
G
E
G
H
Honey Bee
Apis mellifera
XP_623669
404
44652
S30
E
G
S
F
L
F
T
S
E
S
V
G
E
G
H
Nematode Worm
Caenorhab. elegans
P50305
404
44016
S14
L
F
T
S
E
S
V
S
E
G
H
P
D
K
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
A9PDZ7
393
42904
E13
F
T
S
E
S
V
N
E
G
H
P
D
K
L
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUT2
393
42777
E13
F
T
S
E
S
V
N
E
G
H
P
D
K
L
C
Baker's Yeast
Sacchar. cerevisiae
P10659
382
41800
G13
L
F
T
S
E
S
V
G
E
G
H
P
D
K
I
Red Bread Mold
Neurospora crassa
P48466
395
42967
S21
E
G
T
F
L
F
T
S
E
S
V
G
E
G
H
Conservation
Percent
Protein Identity:
100
93.9
84.9
99.7
N.A.
99.4
98.4
N.A.
77.9
84
91.1
82.2
N.A.
71.3
71.7
70.5
N.A.
Protein Similarity:
100
94.1
86.3
100
N.A.
100
99.7
N.A.
82
92.4
97.4
88.3
N.A.
85.5
85.4
81.4
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
20
86.6
93.3
86.6
N.A.
86.6
93.3
20
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
40
93.3
100
86.6
N.A.
86.6
100
26.6
N.A.
Percent
Protein Identity:
64.8
N.A.
N.A.
64.3
66
68.8
Protein Similarity:
76.2
N.A.
N.A.
78.2
81.5
83
P-Site Identity:
0
N.A.
N.A.
0
13.3
100
P-Site Similarity:
13.3
N.A.
N.A.
13.3
20
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
0
0
0
6
12
% C
% Asp:
6
6
0
0
0
0
0
6
0
0
0
12
12
0
0
% D
% Glu:
59
0
0
12
12
0
0
12
83
0
0
0
65
0
0
% E
% Phe:
12
12
0
65
0
65
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
59
6
0
0
0
0
6
12
12
0
71
0
65
6
% G
% His:
0
0
0
0
0
0
6
0
0
12
12
0
6
0
65
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% K
% Leu:
12
0
0
0
59
0
0
0
0
0
6
6
0
18
6
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
0
6
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
6
0
6
0
0
0
0
12
12
0
0
0
% P
% Gln:
0
0
6
6
0
0
0
0
0
0
0
0
6
0
0
% Q
% Arg:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
24
12
12
12
0
77
0
65
0
0
0
0
0
% S
% Thr:
0
12
53
0
6
0
65
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
18
12
0
6
12
65
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _