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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAT2A All Species: 44.85
Human Site: S24 Identified Species: 61.67
UniProt: P31153 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31153 NP_005902.1 395 43661 S24 T F L F T S E S V G E G H P D
Chimpanzee Pan troglodytes XP_515585 413 45605 S24 T F L F T S E S V G E G H P D
Rhesus Macaque Macaca mulatta XP_001083990 438 48324 V67 G P M P R D V V W L H C L S D
Dog Lupus familis XP_532980 395 43656 S24 T F L F T S E S V G E G H P D
Cat Felis silvestris
Mouse Mus musculus Q3THS6 395 43670 S24 T F L F T S E S V G E G H P D
Rat Rattus norvegicus P18298 395 43697 S24 T F L F T S E S V G E G H P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508946 392 42919 V17 Q Q T V H S E V L G Q L G Q R
Chicken Gallus gallus XP_421512 396 43734 S25 A F M F T S E S V G E G H P D
Frog Xenopus laevis NP_001080175 396 43767 S25 S F L F T S E S V G E G H P D
Zebra Danio Brachydanio rerio NP_001014318 363 40041 S25 C F L F T S E S V G E G H P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40320 408 44678 S35 T F L F T S E S V G E G H P D
Honey Bee Apis mellifera XP_623669 404 44652 S32 S F L F T S E S V G E G H P D
Nematode Worm Caenorhab. elegans P50305 404 44016 G16 T S E S V S E G H P D K M C D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa A9PDZ7 393 42904 H15 S E S V N E G H P D K L C D Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LUT2 393 42777 H15 S E S V N E G H P D K L C D Q
Baker's Yeast Sacchar. cerevisiae P10659 382 41800 G15 T S E S V G E G H P D K I C D
Red Bread Mold Neurospora crassa P48466 395 42967 S23 T F L F T S E S V G E G H P D
Conservation
Percent
Protein Identity: 100 93.9 84.9 99.7 N.A. 99.4 98.4 N.A. 77.9 84 91.1 82.2 N.A. 71.3 71.7 70.5 N.A.
Protein Similarity: 100 94.1 86.3 100 N.A. 100 99.7 N.A. 82 92.4 97.4 88.3 N.A. 85.5 85.4 81.4 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 20 86.6 93.3 93.3 N.A. 100 93.3 26.6 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 33.3 93.3 100 93.3 N.A. 100 100 33.3 N.A.
Percent
Protein Identity: 64.8 N.A. N.A. 64.3 66 68.8
Protein Similarity: 76.2 N.A. N.A. 78.2 81.5 83
P-Site Identity: 0 N.A. N.A. 0 20 100
P-Site Similarity: 13.3 N.A. N.A. 13.3 26.6 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 6 12 12 0 % C
% Asp: 0 0 0 0 0 6 0 0 0 12 12 0 0 12 83 % D
% Glu: 0 12 12 0 0 12 83 0 0 0 65 0 0 0 0 % E
% Phe: 0 65 0 65 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 6 0 0 0 0 6 12 12 0 71 0 65 6 0 0 % G
% His: 0 0 0 0 6 0 0 12 12 0 6 0 65 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % K
% Leu: 0 0 59 0 0 0 0 0 6 6 0 18 6 0 0 % L
% Met: 0 0 12 0 0 0 0 0 0 0 0 0 6 0 0 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 6 0 6 0 0 0 0 12 12 0 0 0 65 0 % P
% Gln: 6 6 0 0 0 0 0 0 0 0 6 0 0 6 12 % Q
% Arg: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 6 % R
% Ser: 24 12 12 12 0 77 0 65 0 0 0 0 0 6 0 % S
% Thr: 53 0 6 0 65 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 18 12 0 6 12 65 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _