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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAT2A
All Species:
66.97
Human Site:
S283
Identified Species:
92.08
UniProt:
P31153
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31153
NP_005902.1
395
43661
S283
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Chimpanzee
Pan troglodytes
XP_515585
413
45605
S283
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Rhesus Macaque
Macaca mulatta
XP_001083990
438
48324
S326
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Dog
Lupus familis
XP_532980
395
43656
S283
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3THS6
395
43670
S283
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Rat
Rattus norvegicus
P18298
395
43697
S283
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508946
392
42919
S280
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Chicken
Gallus gallus
XP_421512
396
43734
S284
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Frog
Xenopus laevis
NP_001080175
396
43767
S284
A
H
G
G
G
A
F
S
G
K
D
Y
T
K
V
Zebra Danio
Brachydanio rerio
NP_001014318
363
40041
I267
A
G
L
T
G
R
K
I
I
V
D
T
Y
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40320
408
44678
S294
A
H
G
G
G
A
F
S
G
K
D
F
T
K
V
Honey Bee
Apis mellifera
XP_623669
404
44652
S291
A
H
G
G
G
A
F
S
G
K
D
F
T
K
V
Nematode Worm
Caenorhab. elegans
P50305
404
44016
S271
A
H
G
G
G
A
F
S
G
K
D
P
T
K
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
A9PDZ7
393
42904
S271
A
H
G
G
G
A
F
S
G
K
D
P
T
K
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUT2
393
42777
S271
A
H
G
G
G
A
F
S
G
K
D
P
T
K
V
Baker's Yeast
Sacchar. cerevisiae
P10659
382
41800
S270
S
V
G
G
G
A
F
S
G
K
D
Y
S
K
V
Red Bread Mold
Neurospora crassa
P48466
395
42967
S282
A
H
G
G
G
A
F
S
G
K
D
F
S
K
V
Conservation
Percent
Protein Identity:
100
93.9
84.9
99.7
N.A.
99.4
98.4
N.A.
77.9
84
91.1
82.2
N.A.
71.3
71.7
70.5
N.A.
Protein Similarity:
100
94.1
86.3
100
N.A.
100
99.7
N.A.
82
92.4
97.4
88.3
N.A.
85.5
85.4
81.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
20
N.A.
93.3
93.3
93.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
20
N.A.
100
100
93.3
N.A.
Percent
Protein Identity:
64.8
N.A.
N.A.
64.3
66
68.8
Protein Similarity:
76.2
N.A.
N.A.
78.2
81.5
83
P-Site Identity:
93.3
N.A.
N.A.
93.3
80
86.6
P-Site Similarity:
93.3
N.A.
N.A.
93.3
93.3
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
95
0
0
0
0
95
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
95
0
0
0
0
18
0
0
0
% F
% Gly:
0
6
95
95
100
0
0
0
95
0
0
0
0
6
6
% G
% His:
0
89
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
6
6
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
6
0
0
95
0
0
0
95
0
% K
% Leu:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
18
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
0
0
0
0
0
0
95
0
0
0
0
12
0
0
% S
% Thr:
0
0
0
6
0
0
0
0
0
0
0
6
83
0
0
% T
% Val:
0
6
0
0
0
0
0
0
0
6
0
0
0
0
95
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
59
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _