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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAT2A
All Species:
62.12
Human Site:
Y188
Identified Species:
85.42
UniProt:
P31153
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31153
NP_005902.1
395
43661
Y188
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Chimpanzee
Pan troglodytes
XP_515585
413
45605
Y188
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Rhesus Macaque
Macaca mulatta
XP_001083990
438
48324
Y231
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Dog
Lupus familis
XP_532980
395
43656
Y188
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3THS6
395
43670
Y188
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Rat
Rattus norvegicus
P18298
395
43697
Y188
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508946
392
42919
Y185
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Chicken
Gallus gallus
XP_421512
396
43734
Y189
K
T
Q
V
T
V
Q
Y
I
Q
E
N
G
A
V
Frog
Xenopus laevis
NP_001080175
396
43767
Y189
K
T
Q
V
T
V
Q
Y
M
Q
D
R
G
A
V
Zebra Danio
Brachydanio rerio
NP_001014318
363
40041
T186
P
D
S
K
T
Q
V
T
V
Q
Y
R
Q
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40320
408
44678
Y199
K
T
Q
V
T
C
E
Y
L
F
N
Q
G
S
A
Honey Bee
Apis mellifera
XP_623669
404
44652
Y196
K
T
Q
V
T
C
E
Y
V
M
D
H
G
A
C
Nematode Worm
Caenorhab. elegans
P50305
404
44016
Y176
K
T
Q
V
T
I
E
Y
A
S
E
G
G
A
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
A9PDZ7
393
42904
Y176
K
T
Q
V
T
V
E
Y
L
N
E
N
G
A
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUT2
393
42777
Y176
K
T
Q
V
T
I
E
Y
I
N
E
S
G
A
M
Baker's Yeast
Sacchar. cerevisiae
P10659
382
41800
Y175
K
T
Q
V
T
V
E
Y
K
D
D
H
G
R
W
Red Bread Mold
Neurospora crassa
P48466
395
42967
Y187
K
T
Q
V
T
I
E
Y
K
H
D
N
G
A
V
Conservation
Percent
Protein Identity:
100
93.9
84.9
99.7
N.A.
99.4
98.4
N.A.
77.9
84
91.1
82.2
N.A.
71.3
71.7
70.5
N.A.
Protein Similarity:
100
94.1
86.3
100
N.A.
100
99.7
N.A.
82
92.4
97.4
88.3
N.A.
85.5
85.4
81.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
80
100
20
N.A.
46.6
60
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
26.6
N.A.
80
73.3
73.3
N.A.
Percent
Protein Identity:
64.8
N.A.
N.A.
64.3
66
68.8
Protein Similarity:
76.2
N.A.
N.A.
78.2
81.5
83
P-Site Identity:
60
N.A.
N.A.
53.3
60
66.6
P-Site Similarity:
86.6
N.A.
N.A.
86.6
66.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
6
0
0
0
0
83
6
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
6
0
0
0
0
0
0
0
6
65
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
42
0
0
0
24
0
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
6
95
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
6
0
12
0
0
6
% H
% Ile:
0
0
0
0
0
18
0
0
12
0
0
0
0
0
0
% I
% Lys:
95
0
0
6
0
0
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
48
6
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
6
18
0
0
0
% N
% Pro:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
95
0
0
6
53
0
0
59
0
6
6
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
53
0
6
0
% R
% Ser:
0
0
6
0
0
0
0
0
0
6
0
6
0
6
0
% S
% Thr:
0
95
0
0
100
0
0
6
0
0
0
0
0
0
0
% T
% Val:
0
0
0
95
0
65
6
0
12
0
0
0
0
0
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% W
% Tyr:
0
0
0
0
0
0
0
95
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _