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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAT2A
All Species:
55.76
Human Site:
Y335
Identified Species:
76.67
UniProt:
P31153
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31153
NP_005902.1
395
43661
Y335
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Chimpanzee
Pan troglodytes
XP_515585
413
45605
Y335
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Rhesus Macaque
Macaca mulatta
XP_001083990
438
48324
Y378
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Dog
Lupus familis
XP_532980
395
43656
Y335
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3THS6
395
43670
Y335
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Rat
Rattus norvegicus
P18298
395
43697
Y335
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508946
392
42919
Y332
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Chicken
Gallus gallus
XP_421512
396
43734
Y336
L
S
I
S
L
F
T
Y
G
T
S
Q
K
T
E
Frog
Xenopus laevis
NP_001080175
396
43767
Y336
L
S
I
S
I
F
H
Y
G
T
S
Q
K
S
E
Zebra Danio
Brachydanio rerio
NP_001014318
363
40041
V319
C
R
R
V
L
V
Q
V
S
Y
A
I
G
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40320
408
44678
Y346
L
S
I
T
V
F
D
Y
G
T
S
H
K
S
Q
Honey Bee
Apis mellifera
XP_623669
404
44652
Y343
L
S
I
T
V
F
D
Y
G
T
S
K
L
S
Q
Nematode Worm
Caenorhab. elegans
P50305
404
44016
F323
L
S
V
M
V
F
S
F
G
T
S
A
L
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
A9PDZ7
393
42904
Y323
L
S
V
F
V
D
T
Y
G
T
G
K
I
P
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUT2
393
42777
Y323
L
S
V
F
V
D
S
Y
G
T
G
K
I
P
D
Baker's Yeast
Sacchar. cerevisiae
P10659
382
41800
Y322
L
S
L
H
V
D
T
Y
G
T
A
T
K
S
D
Red Bread Mold
Neurospora crassa
P48466
395
42967
Y334
L
S
I
Y
V
D
T
Y
G
T
S
D
K
T
S
Conservation
Percent
Protein Identity:
100
93.9
84.9
99.7
N.A.
99.4
98.4
N.A.
77.9
84
91.1
82.2
N.A.
71.3
71.7
70.5
N.A.
Protein Similarity:
100
94.1
86.3
100
N.A.
100
99.7
N.A.
82
92.4
97.4
88.3
N.A.
85.5
85.4
81.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
80
100
0
N.A.
66.6
60
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
13.3
N.A.
86.6
86.6
73.3
N.A.
Percent
Protein Identity:
64.8
N.A.
N.A.
64.3
66
68.8
Protein Similarity:
76.2
N.A.
N.A.
78.2
81.5
83
P-Site Identity:
33.3
N.A.
N.A.
33.3
46.6
53.3
P-Site Similarity:
60
N.A.
N.A.
60
73.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
6
0
0
6
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
24
12
0
0
0
0
6
0
0
18
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% E
% Phe:
0
0
0
12
0
71
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
95
0
12
0
6
0
0
% G
% His:
0
0
0
6
0
0
48
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
71
0
48
0
0
0
0
0
0
6
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
18
71
0
0
% K
% Leu:
95
0
6
0
12
0
0
0
0
0
0
0
12
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
6
0
0
0
0
53
0
0
12
% Q
% Arg:
0
6
6
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
95
0
53
0
0
12
0
6
0
77
0
0
65
6
% S
% Thr:
0
0
0
12
0
0
24
0
0
95
0
6
0
12
0
% T
% Val:
0
0
18
6
42
6
0
6
0
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
89
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _