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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRD5A2
All Species:
23.94
Human Site:
Y132
Identified Species:
47.88
UniProt:
P31213
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31213
NP_000339.2
254
28393
Y132
L
Q
G
Y
Y
L
I
Y
C
A
E
Y
P
D
G
Chimpanzee
Pan troglodytes
XP_001144414
211
24056
V92
R
Y
L
S
H
C
A
V
Y
A
D
D
W
V
T
Rhesus Macaque
Macaca mulatta
XP_001105329
254
28485
Y132
L
Q
S
Y
Y
L
I
Y
C
A
E
Y
P
D
G
Dog
Lupus familis
XP_532922
254
28510
Y132
L
Q
G
Y
Y
L
I
Y
C
A
E
Y
P
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99N99
254
28600
Y132
L
Q
A
Y
Y
L
V
Y
C
A
E
Y
P
E
E
Rat
Rattus norvegicus
P31214
254
28753
Y132
L
Q
A
Y
Y
L
V
Y
C
A
E
Y
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509315
164
18777
E45
Y
Y
L
T
Y
C
A
E
Y
P
D
D
W
Y
T
Chicken
Gallus gallus
XP_001235447
255
29637
Y133
L
Q
G
Y
Y
L
I
Y
C
A
E
Y
P
N
D
Frog
Xenopus laevis
Q8AVI9
319
36573
V132
L
G
G
E
L
S
V
V
L
A
F
S
L
L
W
Zebra Danio
Brachydanio rerio
NP_001017703
252
28724
T132
G
H
Y
M
L
H
C
T
Q
Y
S
S
D
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510071
243
28161
Y124
L
Q
G
V
W
N
S
Y
Y
Q
L
E
E
E
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38944
262
30616
Y139
Q
A
R
W
V
S
H
Y
K
D
D
Y
E
D
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.6
95.6
84.2
N.A.
75.1
77.5
N.A.
51.1
66.6
23.8
53.5
N.A.
N.A.
N.A.
40.1
N.A.
Protein Similarity:
100
57
97.2
90.9
N.A.
84.6
85.8
N.A.
58.6
76.8
36.9
70.4
N.A.
N.A.
N.A.
54.7
N.A.
P-Site Identity:
100
6.6
93.3
86.6
N.A.
73.3
73.3
N.A.
6.6
86.6
20
0
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
20
93.3
86.6
N.A.
86.6
86.6
N.A.
13.3
93.3
26.6
0
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
0
0
0
17
0
0
67
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
17
9
0
50
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
25
17
9
25
9
% D
% Glu:
0
0
0
9
0
0
0
9
0
0
50
9
17
25
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
9
42
0
0
0
0
0
0
0
0
0
0
0
25
% G
% His:
0
9
0
0
9
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
67
0
17
0
17
50
0
0
9
0
9
0
9
9
17
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
50
0
0
% P
% Gln:
9
59
0
0
0
0
0
0
9
9
0
0
0
0
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
9
0
17
9
0
0
0
9
17
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
17
% T
% Val:
0
0
0
9
9
0
25
17
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
9
9
0
0
0
0
0
0
0
17
9
9
% W
% Tyr:
9
17
9
50
59
0
0
67
25
9
0
59
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _