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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRD5A2
All Species:
22.12
Human Site:
Y242
Identified Species:
44.24
UniProt:
P31213
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31213
NP_000339.2
254
28393
Y242
Y
L
K
M
F
E
D
Y
P
K
S
R
K
A
L
Chimpanzee
Pan troglodytes
XP_001144414
211
24056
K201
R
K
F
E
E
Y
P
K
F
R
K
I
I
I
P
Rhesus Macaque
Macaca mulatta
XP_001105329
254
28485
Y242
Y
L
K
M
F
E
D
Y
P
K
S
R
K
A
L
Dog
Lupus familis
XP_532922
254
28510
Y242
Y
L
K
M
F
E
D
Y
P
K
S
R
K
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99N99
254
28600
Y242
Y
L
K
M
F
K
D
Y
P
K
S
R
K
A
L
Rat
Rattus norvegicus
P31214
254
28753
Y242
Y
L
K
M
F
K
D
Y
P
K
S
R
K
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509315
164
18777
K154
E
V
F
P
N
Y
P
K
S
R
K
A
L
I
P
Chicken
Gallus gallus
XP_001235447
255
29637
Y243
Y
L
K
T
F
T
D
Y
P
K
S
R
K
A
L
Frog
Xenopus laevis
Q8AVI9
319
36573
D305
E
F
Y
H
E
K
F
D
S
Y
P
I
H
R
K
Zebra Danio
Brachydanio rerio
NP_001017703
252
28724
P241
L
E
K
F
K
D
Y
P
K
S
R
K
A
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510071
243
28161
P233
E
K
F
P
K
Y
P
P
T
R
R
A
L
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38944
262
30616
E249
Y
I
A
K
F
K
E
E
Y
P
K
T
R
K
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.6
95.6
84.2
N.A.
75.1
77.5
N.A.
51.1
66.6
23.8
53.5
N.A.
N.A.
N.A.
40.1
N.A.
Protein Similarity:
100
57
97.2
90.9
N.A.
84.6
85.8
N.A.
58.6
76.8
36.9
70.4
N.A.
N.A.
N.A.
54.7
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
0
86.6
0
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
86.6
6.6
26.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
17
9
50
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
50
9
0
0
0
0
0
0
0
% D
% Glu:
25
9
0
9
17
25
9
9
0
0
0
0
0
0
0
% E
% Phe:
0
9
25
9
59
0
9
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
17
9
25
9
% I
% Lys:
0
17
59
9
17
34
0
17
9
50
25
9
50
9
9
% K
% Leu:
9
50
0
0
0
0
0
0
0
0
0
0
17
0
50
% L
% Met:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
17
0
0
25
17
50
9
9
0
0
0
25
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
25
17
50
9
9
0
% R
% Ser:
0
0
0
0
0
0
0
0
17
9
50
0
0
0
0
% S
% Thr:
0
0
0
9
0
9
0
0
9
0
0
9
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
59
0
9
0
0
25
9
50
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _