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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOXA11 All Species: 22.42
Human Site: T249 Identified Species: 49.33
UniProt: P31270 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31270 NP_005514.1 313 34486 T249 R K K R C P Y T K Y Q I R E L
Chimpanzee Pan troglodytes XP_519012 299 32932 E245 Q I R E L E R E F F F S V Y I
Rhesus Macaque Macaca mulatta A2D635 342 38100 T276 R K K R C P Y T K H Q T L E L
Dog Lupus familis XP_854157 705 74640 T639 R K K R C P Y T K H Q T L E L
Cat Felis silvestris
Mouse Mus musculus P31311 313 34466 T249 R K K R C P Y T K Y Q I R E L
Rat Rattus norvegicus NP_001123350 313 34465 T249 R K K R C P Y T K Y Q I R E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509556 325 35756 T261 R K K R C P Y T K Y Q I R E L
Chicken Gallus gallus P31258 297 33254 F244 I R E L E R E F F F S V Y I N
Frog Xenopus laevis P31272 232 26220 T179 C P Y S K Y Q T L E L E K E F
Zebra Danio Brachydanio rerio Q9DDU1 283 32296 F230 I R E L E R E F F F S V Y I N
Tiger Blowfish Takifugu rubipres Q1KL17 283 32069 F230 I R E L E R E F F F S V Y I N
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.6 25.4 38.1 N.A. 97.4 97.4 N.A. 80.9 81.4 29.7 65.1 56.5 N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.1 39.4 41.1 N.A. 98 98 N.A. 86.4 86.9 43.1 76 64.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 80 80 N.A. 100 100 N.A. 100 0 13.3 0 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 86.6 86.6 N.A. 100 100 N.A. 100 26.6 20 26.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 10 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 28 10 28 10 28 10 0 10 0 10 0 64 0 % E
% Phe: 0 0 0 0 0 0 0 28 37 37 10 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % H
% Ile: 28 10 0 0 0 0 0 0 0 0 0 37 0 28 10 % I
% Lys: 0 55 55 0 10 0 0 0 55 0 0 0 10 0 0 % K
% Leu: 0 0 0 28 10 0 0 0 10 0 10 0 19 0 55 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 % N
% Pro: 0 10 0 0 0 55 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 0 55 0 0 0 0 % Q
% Arg: 55 28 10 55 0 28 10 0 0 0 0 0 37 0 0 % R
% Ser: 0 0 0 10 0 0 0 0 0 0 28 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 64 0 0 0 19 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 28 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 10 55 0 0 37 0 0 28 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _