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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOXC12
All Species:
41.82
Human Site:
Y221
Identified Species:
92
UniProt:
P31275
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31275
NP_776272.1
282
30171
Y221
S
R
K
K
R
K
P
Y
S
K
L
Q
L
A
E
Chimpanzee
Pan troglodytes
XP_522409
280
30071
Y219
S
R
K
K
R
K
P
Y
S
K
L
Q
L
A
E
Rhesus Macaque
Macaca mulatta
A2D635
342
38100
Y275
G
R
K
K
R
C
P
Y
T
K
H
Q
T
L
E
Dog
Lupus familis
XP_543628
277
29882
Y216
S
R
K
K
R
K
P
Y
S
K
L
Q
L
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K5B8
280
30326
Y219
S
R
K
K
R
K
P
Y
S
K
L
Q
L
A
E
Rat
Rattus norvegicus
NP_001100266
280
30289
Y219
S
R
K
K
R
K
P
Y
S
K
L
Q
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511494
270
28958
Y209
A
R
K
K
R
K
P
Y
T
K
Q
Q
I
A
E
Chicken
Gallus gallus
P24343
266
29995
Y205
S
R
K
K
R
K
P
Y
T
K
Q
Q
I
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9YGT0
283
31555
Y222
T
R
K
K
R
K
P
Y
S
K
L
Q
L
N
E
Tiger Blowfish
Takifugu rubipres
Q1KKV3
275
30717
Y214
T
R
K
K
R
K
P
Y
S
K
L
Q
L
A
E
Fruit Fly
Dros. melanogaster
P09087
493
55078
Y394
V
R
K
K
R
K
P
Y
S
K
F
Q
T
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
27.4
93.2
N.A.
95.3
96
N.A.
44.6
39.3
N.A.
53.3
67.7
21.1
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
39.4
94.3
N.A.
96
96.8
N.A.
56.7
53.9
N.A.
64.6
76.6
32.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
100
N.A.
100
100
N.A.
73.3
80
N.A.
86.6
93.3
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
100
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
73
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% I
% Lys:
0
0
100
100
0
91
0
0
0
100
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
64
0
64
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
19
100
0
0
0
% Q
% Arg:
0
100
0
0
100
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
55
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% S
% Thr:
19
0
0
0
0
0
0
0
28
0
0
0
19
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _