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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX1
All Species:
19.09
Human Site:
T260
Identified Species:
46.67
UniProt:
P31314
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31314
NP_005512.1
330
34365
T260
R
T
K
W
R
R
Q
T
A
E
E
R
E
A
E
Chimpanzee
Pan troglodytes
A2T756
283
30712
Q225
G
G
V
A
E
P
E
Q
D
C
A
V
T
S
G
Rhesus Macaque
Macaca mulatta
XP_001109904
336
34781
T266
R
T
K
W
R
R
Q
T
A
E
E
R
E
A
E
Dog
Lupus familis
XP_850598
337
34575
T267
R
T
K
W
R
R
Q
T
A
E
E
R
E
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P43345
332
34626
T262
R
T
K
W
R
R
Q
T
A
E
E
R
E
A
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
T269
R
T
K
W
R
R
Q
T
A
E
E
R
E
A
E
Chicken
Gallus gallus
O93366
297
32407
A238
R
E
A
E
R
Q
Q
A
N
R
I
L
M
Q
L
Frog
Xenopus laevis
Q2PYN8
267
29567
T209
S
A
V
E
A
V
L
T
I
S
E
L
E
E
S
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
A235
Q
L
A
A
E
L
E
A
A
N
L
S
H
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26656
405
44721
M312
R
N
K
W
K
R
Q
M
A
A
E
L
E
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.4
96.4
94.6
N.A.
93.6
N.A.
N.A.
74.1
73.6
22.1
21.5
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
37.8
96.4
94.9
N.A.
94.8
N.A.
N.A.
78.4
79
38.1
36
N.A.
N.A.
N.A.
N.A.
35
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
100
20
20
13.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
100
26.6
20
26.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
20
20
10
0
0
20
70
10
10
0
0
60
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
0
20
20
0
20
0
0
50
70
0
70
10
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
0
60
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
10
10
0
0
0
10
30
0
0
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
10
70
10
0
0
0
0
0
10
0
% Q
% Arg:
70
0
0
0
60
60
0
0
0
10
0
50
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
10
0
10
0
20
10
% S
% Thr:
0
50
0
0
0
0
0
60
0
0
0
0
10
0
0
% T
% Val:
0
0
20
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _