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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1B
All Species:
50.61
Human Site:
Y373
Identified Species:
79.52
UniProt:
P31321
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31321
NP_002726.1
381
43073
Y373
L
K
R
N
I
Q
R
Y
N
S
F
I
S
L
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083834
375
41914
Y367
L
K
R
N
I
Q
R
Y
N
S
F
I
S
L
T
Dog
Lupus familis
XP_537920
377
42817
Y369
L
K
R
N
I
Q
R
Y
N
S
F
I
S
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P12849
381
43206
Y373
L
K
R
N
I
Q
R
Y
N
S
F
I
S
L
T
Rat
Rattus norvegicus
P81377
381
43264
Y373
L
K
R
N
I
Q
R
Y
N
S
F
I
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
Y618
L
K
R
N
I
Q
Q
Y
N
S
F
V
S
L
S
Chicken
Gallus gallus
Q5ZM91
382
43332
Y374
L
K
R
N
I
Q
Q
Y
N
S
F
V
S
L
S
Frog
Xenopus laevis
NP_001085084
381
43157
Y373
L
K
R
N
I
Q
Q
Y
N
S
F
V
S
L
S
Zebra Danio
Brachydanio rerio
NP_001070091
380
42942
Y372
L
K
R
N
I
Q
R
Y
N
S
F
I
S
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
Y368
L
K
R
N
I
T
Q
Y
N
S
F
V
S
L
S
Honey Bee
Apis mellifera
XP_396167
372
41646
Y364
L
K
R
N
I
T
Q
Y
N
S
F
V
S
L
S
Nematode Worm
Caenorhab. elegans
P30625
366
41449
Y358
L
K
R
D
V
S
N
Y
N
S
Y
V
K
L
M
Sea Urchin
Strong. purpuratus
Q26619
369
41770
Y359
M
K
R
N
I
E
H
Y
E
Q
E
T
S
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
K409
G
P
A
V
D
V
L
K
L
N
D
P
T
R
H
Red Bread Mold
Neurospora crassa
Q01386
385
42138
E375
L
R
R
T
R
Y
V
E
A
E
E
V
D
P
L
Conservation
Percent
Protein Identity:
100
N.A.
72.9
93.9
N.A.
95
95
N.A.
52
82.9
83.1
92.9
N.A.
71.6
72.9
57.7
39.6
Protein Similarity:
100
N.A.
81
96.5
N.A.
98.6
98.6
N.A.
57.6
92.1
91
97.1
N.A.
84.2
84.7
73.2
56.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
80
80
80
100
N.A.
73.3
73.3
46.6
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
93.3
73.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
32.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.2
51.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
0
0
7
0
7
0
0
% D
% Glu:
0
0
0
0
0
7
0
7
7
7
14
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
74
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
80
0
0
0
0
0
0
40
0
0
0
% I
% Lys:
0
87
0
0
0
0
0
7
0
0
0
0
7
0
0
% K
% Leu:
87
0
0
0
0
0
7
0
7
0
0
0
0
80
14
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
80
0
0
7
0
80
7
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
7
0
7
0
% P
% Gln:
0
0
0
0
0
60
34
0
0
7
0
0
0
0
0
% Q
% Arg:
0
7
94
0
7
0
40
0
0
0
0
0
0
14
0
% R
% Ser:
0
0
0
0
0
7
0
0
0
80
0
0
80
0
34
% S
% Thr:
0
0
0
7
0
14
0
0
0
0
0
7
7
0
40
% T
% Val:
0
0
0
7
7
7
7
0
0
0
0
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
87
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _