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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
33.64
Human Site:
S164
Identified Species:
49.33
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
S164
N
L
D
P
E
Q
M
S
Q
V
L
D
A
M
F
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
S223
N
L
D
P
E
Q
M
S
Q
V
L
D
A
M
F
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
S207
N
L
D
P
E
Q
M
S
Q
V
L
D
A
M
F
Dog
Lupus familis
XP_849179
417
46163
S163
N
L
D
P
E
Q
M
S
Q
V
L
D
A
M
F
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
S162
N
L
D
P
E
Q
M
S
Q
V
L
D
A
M
F
Rat
Rattus norvegicus
P12369
416
46104
S162
N
L
D
P
E
Q
M
S
Q
V
L
D
A
M
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
F96
Q
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
Chicken
Gallus gallus
Q5ZM91
382
43332
S148
H
L
D
D
N
E
R
S
D
I
F
D
A
M
F
Frog
Xenopus laevis
NP_001084637
402
45172
S148
N
L
D
Q
E
Q
M
S
Q
V
L
D
A
M
F
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
S146
A
L
D
Q
E
Q
F
S
E
V
L
D
A
M
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
R143
V
L
D
A
M
F
E
R
K
V
Q
P
G
D
F
Honey Bee
Apis mellifera
XP_392905
383
43849
G149
F
E
K
I
V
K
S
G
E
I
V
I
R
Q
G
Nematode Worm
Caenorhab. elegans
P30625
366
41449
F139
K
T
M
Y
D
A
M
F
P
V
E
K
S
A
G
Sea Urchin
Strong. purpuratus
Q26619
369
41770
K140
V
I
D
A
M
F
E
K
K
T
T
P
G
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
Q173
E
K
S
E
Q
Q
L
Q
R
L
E
K
S
I
R
Red Bread Mold
Neurospora crassa
Q01386
385
42138
A152
L
V
E
K
P
V
P
A
K
G
I
K
V
I
T
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
46.6
93.3
73.3
N.A.
26.6
0
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
66.6
93.3
80
N.A.
33.3
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
13
0
7
0
7
0
0
0
0
57
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
75
13
7
7
0
0
7
0
0
63
0
13
0
% D
% Glu:
7
7
7
7
50
7
13
0
13
0
13
0
0
0
0
% E
% Phe:
7
0
0
0
0
13
7
13
0
0
7
0
0
0
63
% F
% Gly:
0
7
0
0
7
0
0
7
0
7
0
0
13
7
13
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
7
0
7
0
0
0
0
0
13
13
7
0
13
0
% I
% Lys:
7
7
7
7
0
7
0
7
19
0
0
19
0
0
0
% K
% Leu:
7
63
0
0
0
0
7
0
0
7
50
0
0
0
0
% L
% Met:
0
0
7
0
13
0
50
0
0
0
0
0
0
57
0
% M
% Asn:
44
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
38
7
0
7
0
7
0
0
13
0
0
0
% P
% Gln:
7
0
0
13
7
57
0
7
44
0
7
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
7
7
7
0
0
0
13
0
7
% R
% Ser:
0
0
7
0
0
0
7
57
0
0
0
0
13
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
7
7
0
0
0
13
% T
% Val:
13
7
0
0
7
7
0
0
0
69
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _