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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
36.06
Human Site:
S279
Identified Species:
52.89
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
S279
E
S
L
P
F
L
K
S
L
E
F
S
E
R
L
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
S338
E
S
L
P
F
L
K
S
L
E
F
S
E
R
L
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
S322
E
S
L
P
F
L
K
S
L
E
F
S
E
R
L
Dog
Lupus familis
XP_849179
417
46163
S278
E
S
L
P
F
L
K
S
L
E
V
S
E
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
S277
E
S
L
P
F
L
K
S
L
E
V
S
E
R
L
Rat
Rattus norvegicus
P12369
416
46104
S277
E
S
L
P
F
L
K
S
L
E
V
S
E
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
I197
R
L
K
V
V
D
V
I
G
T
K
I
Y
K
D
Chicken
Gallus gallus
Q5ZM91
382
43332
V254
Y
E
E
F
L
S
K
V
S
I
L
E
S
L
D
Frog
Xenopus laevis
NP_001084637
402
45172
S263
E
S
L
P
F
L
K
S
L
E
F
S
E
R
L
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
S261
E
S
I
P
L
L
K
S
L
E
L
S
E
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
A245
N
S
V
P
M
L
K
A
L
Q
N
Y
E
R
M
Honey Bee
Apis mellifera
XP_392905
383
43849
S251
N
K
V
P
M
L
K
S
L
E
P
Y
E
R
M
Nematode Worm
Caenorhab. elegans
P30625
366
41449
I240
E
F
L
S
K
V
Q
I
L
A
D
L
D
Q
W
Sea Urchin
Strong. purpuratus
Q26619
369
41770
S242
E
K
V
S
I
F
K
S
L
E
P
Y
E
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
G284
T
F
R
K
I
L
L
G
S
S
F
K
K
R
L
Red Bread Mold
Neurospora crassa
Q01386
385
42138
F255
R
R
R
M
Y
E
S
F
L
E
E
V
P
I
L
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
6.6
100
73.3
N.A.
46.6
53.3
20
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
6.6
100
86.6
N.A.
73.3
66.6
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
7
0
7
0
13
% D
% Glu:
63
7
7
0
0
7
0
0
0
69
7
7
69
0
0
% E
% Phe:
0
13
0
7
44
7
0
7
0
0
32
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
13
0
0
13
0
7
0
7
0
7
0
% I
% Lys:
0
13
7
7
7
0
75
0
0
0
7
7
7
7
0
% K
% Leu:
0
7
50
0
13
69
7
0
82
0
13
7
0
7
57
% L
% Met:
0
0
0
7
13
0
0
0
0
0
0
0
0
0
25
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
63
0
0
0
0
0
0
13
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
7
0
0
0
7
0
% Q
% Arg:
13
7
13
0
0
0
0
0
0
0
0
0
0
75
0
% R
% Ser:
0
57
0
13
0
7
7
63
13
7
0
50
7
0
0
% S
% Thr:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
0
0
19
7
7
7
7
7
0
0
19
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
0
0
7
0
0
0
0
0
0
19
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _