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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
37.58
Human Site:
S364
Identified Species:
55.11
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
S364
T
N
K
P
R
A
A
S
A
H
A
I
G
T
V
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
S423
T
N
K
P
R
A
A
S
A
H
A
I
G
T
V
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
S407
T
N
K
P
R
A
A
S
A
H
A
I
G
T
V
Dog
Lupus familis
XP_849179
417
46163
S363
T
N
K
P
R
A
A
S
A
H
A
I
G
T
V
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
S362
T
N
K
P
R
A
A
S
A
H
A
I
G
T
V
Rat
Rattus norvegicus
P12369
416
46104
S362
T
N
K
P
R
A
A
S
A
H
A
I
G
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
D282
T
V
K
C
L
A
M
D
V
Q
A
F
E
R
L
Chicken
Gallus gallus
Q5ZM91
382
43332
T339
M
N
R
P
R
A
A
T
V
V
A
R
G
L
L
Frog
Xenopus laevis
NP_001084637
402
45172
S348
T
N
K
P
R
A
A
S
A
Y
A
V
G
N
V
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
S346
T
N
K
P
R
A
A
S
A
Y
A
I
G
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
V330
S
V
Y
A
T
G
G
V
V
K
L
A
F
L
D
Honey Bee
Apis mellifera
XP_392905
383
43849
E336
A
S
A
Y
A
V
G
E
V
K
L
A
F
L
D
Nematode Worm
Caenorhab. elegans
P30625
366
41449
V325
R
P
R
A
A
T
V
V
A
K
T
H
L
K
C
Sea Urchin
Strong. purpuratus
Q26619
369
41770
Y327
K
P
R
A
A
S
V
Y
A
V
E
D
V
D
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
V369
D
H
D
Y
F
G
E
V
A
L
L
N
D
L
P
Red Bread Mold
Neurospora crassa
Q01386
385
42138
S340
N
D
A
P
R
A
A
S
V
I
S
Q
T
E
V
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
26.6
46.6
80
86.6
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
66.6
93.3
93.3
N.A.
6.6
6.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
19
19
69
63
0
69
0
63
13
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
13
% C
% Asp:
7
7
7
0
0
0
0
7
0
0
0
7
7
13
13
% D
% Glu:
0
0
0
0
0
0
7
7
0
0
7
0
7
7
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
7
13
0
0
% F
% Gly:
0
0
0
0
0
13
13
0
0
0
0
0
57
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
38
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
44
0
0
0
% I
% Lys:
7
0
57
0
0
0
0
0
0
19
0
0
0
7
0
% K
% Leu:
0
0
0
0
7
0
0
0
0
7
19
0
7
25
13
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
57
0
0
0
0
0
0
0
0
0
7
0
7
0
% N
% Pro:
0
13
0
63
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% Q
% Arg:
7
0
19
0
63
0
0
0
0
0
0
7
0
7
0
% R
% Ser:
7
7
0
0
0
7
0
57
0
0
7
0
0
0
0
% S
% Thr:
57
0
0
0
7
7
0
7
0
0
7
0
7
38
0
% T
% Val:
0
13
0
0
0
7
13
19
32
13
0
7
7
0
57
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
13
0
0
0
7
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _