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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
24.55
Human Site:
T138
Identified Species:
36
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
T138
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
T197
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
T181
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Dog
Lupus familis
XP_849179
417
46163
T137
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
T136
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Rat
Rattus norvegicus
P12369
416
46104
T136
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
K81
A
M
F
E
K
L
V
K
E
G
E
H
V
I
D
Chicken
Gallus gallus
Q5ZM91
382
43332
K124
K
V
I
P
K
D
Y
K
T
M
A
A
L
A
K
Frog
Xenopus laevis
NP_001084637
402
45172
L129
T
D
D
Q
R
N
R
L
Q
E
A
C
T
D
I
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
Q128
D
E
Q
R
C
R
L
Q
E
A
C
K
D
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
S127
K
N
V
L
L
F
R
S
L
E
K
E
Q
M
N
Honey Bee
Apis mellifera
XP_392905
383
43849
M134
R
S
L
D
E
D
Q
M
T
D
V
L
D
A
M
Nematode Worm
Caenorhab. elegans
P30625
366
41449
A124
M
R
K
N
L
L
F
A
H
L
E
E
D
E
Q
Sea Urchin
Strong. purpuratus
Q26619
369
41770
L125
N
I
L
L
F
R
A
L
D
E
K
Q
M
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
E149
R
R
T
S
V
S
G
E
T
L
Q
P
N
N
F
Red Bread Mold
Neurospora crassa
Q01386
385
42138
E134
N
F
L
F
N
H
L
E
D
D
Q
S
A
Q
V
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
0
6.6
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
6.6
26.6
26.6
N.A.
40
33.3
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
7
0
7
13
7
7
13
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
7
7
0
0
0
% C
% Asp:
7
7
7
7
0
13
0
0
50
50
0
0
19
7
7
% D
% Glu:
0
7
0
7
7
0
0
13
13
19
13
13
0
7
7
% E
% Phe:
0
7
7
7
7
7
7
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
38
7
0
0
7
0
0
7
0
0
0
% H
% Ile:
0
7
44
38
0
0
0
0
0
0
0
0
0
13
7
% I
% Lys:
13
0
7
0
13
0
38
13
0
0
13
7
0
0
7
% K
% Leu:
0
0
19
13
13
13
13
13
7
13
0
7
7
0
44
% L
% Met:
7
7
0
0
0
0
0
7
0
7
0
0
7
7
7
% M
% Asn:
13
7
0
7
7
7
0
0
0
0
0
0
44
7
7
% N
% Pro:
0
0
0
7
0
38
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
7
7
0
0
7
7
7
0
50
7
7
13
7
% Q
% Arg:
13
50
0
7
7
13
13
0
0
0
0
38
0
38
0
% R
% Ser:
38
7
0
7
0
7
0
7
0
0
0
7
0
0
0
% S
% Thr:
7
0
7
0
0
0
0
38
19
0
0
0
7
0
0
% T
% Val:
0
7
7
0
7
0
7
0
0
0
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _