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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
35.15
Human Site:
Y192
Identified Species:
51.56
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
Y192
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
F
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
Y251
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
F
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
Y235
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
Y
Dog
Lupus familis
XP_849179
417
46163
Y191
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
F
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
Y190
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
F
Rat
Rattus norvegicus
P12369
416
46104
Y190
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
D111
F
D
I
Y
V
K
C
D
G
V
G
R
C
V
G
Chicken
Gallus gallus
Q5ZM91
382
43332
Q167
I
A
G
E
T
V
I
Q
Q
G
D
E
G
D
N
Frog
Xenopus laevis
NP_001084637
402
45172
Y176
G
D
D
G
D
N
F
Y
V
I
D
R
G
T
Y
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
Y174
G
D
D
G
D
N
F
Y
V
I
E
R
G
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
G158
I
I
R
Q
G
D
D
G
D
N
F
Y
V
I
E
Honey Bee
Apis mellifera
XP_392905
383
43849
V164
D
D
G
D
N
F
Y
V
I
E
R
G
K
F
E
Nematode Worm
Caenorhab. elegans
P30625
366
41449
E154
E
T
I
I
E
Q
G
E
E
G
D
N
F
Y
V
Sea Urchin
Strong. purpuratus
Q26619
369
41770
G155
V
I
D
Q
G
D
D
G
D
N
F
Y
V
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
R194
K
L
D
S
D
S
K
R
L
V
I
N
C
L
E
Red Bread Mold
Neurospora crassa
Q01386
385
42138
Y168
G
D
A
G
D
Y
F
Y
V
V
E
K
G
R
F
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
13.3
13.3
93.3
80
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
100
93.3
N.A.
6.6
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
13
0
0
% C
% Asp:
7
69
63
7
63
13
13
7
13
0
57
0
0
7
7
% D
% Glu:
7
0
0
7
7
0
0
7
7
7
13
7
0
0
19
% E
% Phe:
7
0
0
0
0
7
57
0
0
0
13
0
7
7
38
% F
% Gly:
57
0
13
57
13
0
7
13
7
13
7
7
63
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
13
13
7
0
0
7
0
7
50
7
0
0
13
0
% I
% Lys:
7
0
0
0
0
7
7
0
0
0
0
7
7
0
0
% K
% Leu:
0
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
50
0
0
0
13
0
13
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
0
7
0
7
7
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
7
0
0
7
57
0
7
0
% R
% Ser:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
7
0
0
7
0
0
0
0
0
0
0
0
44
0
% T
% Val:
7
0
0
0
7
7
0
7
57
19
0
0
13
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
7
7
57
0
0
0
13
0
7
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _