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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPS1 All Species: 35.76
Human Site: S785 Identified Species: 87.41
UniProt: P31327 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31327 NP_001116105.1 1500 164939 S785 L D R F H G T S S R I G S S M
Chimpanzee Pan troglodytes XP_001146674 1500 164827 S785 L D R F H G T S S R I G S S M
Rhesus Macaque Macaca mulatta XP_001110375 1500 164810 S785 L D R F H G T S S R I G S S M
Dog Lupus familis XP_545627 1500 164522 S785 L D R F H G T S S R I G S S M
Cat Felis silvestris
Mouse Mus musculus Q8C196 1500 164599 S785 L D R F H G T S S R I G S S M
Rat Rattus norvegicus P07756 1500 164561 S785 L D R F H G T S S R I G S S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089109 1494 164130 S779 L D R F H G T S G V I G S S M
Zebra Danio Brachydanio rerio XP_683282 1524 168010 S775 L D R F H G M S R E I G S A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P05990 2224 246654 S763 L A K F V R V S K H I G S S M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P07259 2214 245107 S796 L K K F T R V S T E L S S S M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.8 96.2 N.A. 95.3 95.5 N.A. N.A. N.A. 79.1 71 N.A. 36.2 N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.5 98.4 N.A. 98.5 98.5 N.A. N.A. N.A. 89.5 84.5 N.A. 48.7 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 73.3 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 80 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % E
% Phe: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 80 0 0 10 0 0 90 0 0 0 % G
% His: 0 0 0 0 80 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 90 0 0 0 0 % I
% Lys: 0 10 20 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 100 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 100 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 80 0 0 20 0 0 10 60 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 60 0 0 10 100 90 0 % S
% Thr: 0 0 0 0 10 0 70 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 20 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _