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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPS1
All Species:
22.12
Human Site:
Y140
Identified Species:
54.07
UniProt:
P31327
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31327
NP_001116105.1
1500
164939
Y140
V
L
D
Y
S
K
D
Y
N
H
W
L
A
T
K
Chimpanzee
Pan troglodytes
XP_001146674
1500
164827
Y140
V
L
D
Y
S
K
D
Y
N
H
W
L
A
T
K
Rhesus Macaque
Macaca mulatta
XP_001110375
1500
164810
Y140
V
L
D
Y
S
K
D
Y
N
H
W
L
A
T
K
Dog
Lupus familis
XP_545627
1500
164522
Y140
V
L
N
Y
S
D
D
Y
H
H
W
L
A
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C196
1500
164599
Y140
V
L
N
Y
S
N
D
Y
N
H
W
L
A
T
K
Rat
Rattus norvegicus
P07756
1500
164561
Y140
V
L
N
Y
S
H
D
Y
N
H
W
L
A
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089109
1494
164130
S143
W
R
A
V
K
S
L
S
E
W
L
H
E
E
K
Zebra Danio
Brachydanio rerio
XP_683282
1524
168010
Q140
N
S
V
K
S
L
A
Q
W
L
Q
E
E
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05990
2224
246654
L141
T
R
A
L
T
K
K
L
R
E
Q
G
S
M
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07259
2214
245107
H150
D
T
R
S
L
T
K
H
L
R
D
A
G
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.8
96.2
N.A.
95.3
95.5
N.A.
N.A.
N.A.
79.1
71
N.A.
36.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.5
98.4
N.A.
98.5
98.5
N.A.
N.A.
N.A.
89.5
84.5
N.A.
48.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
N.A.
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
10
0
0
0
0
10
60
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
30
0
0
10
60
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
10
0
10
20
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
10
0
10
10
60
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
40
20
0
0
0
0
0
0
10
70
% K
% Leu:
0
60
0
10
10
10
10
10
10
10
10
60
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
10
0
30
0
0
10
0
0
50
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
20
0
0
0
0
% Q
% Arg:
0
20
10
0
0
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
10
0
10
70
10
0
10
0
0
0
0
10
10
0
% S
% Thr:
10
10
0
0
10
10
0
0
0
0
0
0
0
60
0
% T
% Val:
60
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
10
10
60
0
0
0
0
% W
% Tyr:
0
0
0
60
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _