KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM2
All Species:
0
Human Site:
T12
Identified Species:
0
UniProt:
P31350
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31350
NP_001025.1
389
44878
T12
R
V
P
L
A
P
I
T
D
P
Q
Q
L
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100144
351
40744
E8
M
G
D
P
E
R
P
E
A
A
G
L
D
L
D
Dog
Lupus familis
XP_540076
394
45449
Q17
T
I
A
D
P
Q
Q
Q
Q
Q
Q
Q
L
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P11157
390
45077
A12
R
T
P
L
A
T
I
A
D
Q
Q
Q
L
Q
L
Rat
Rattus norvegicus
Q4KLN6
390
45020
A12
R
A
P
L
A
T
I
A
D
Q
Q
Q
L
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506085
394
45462
P16
A
P
L
A
S
K
Q
P
P
Q
P
S
L
R
L
Chicken
Gallus gallus
XP_419948
384
44421
Q12
R
V
P
L
A
A
R
Q
E
Q
P
R
L
S
P
Frog
Xenopus laevis
NP_001080772
386
44577
V15
F
A
Q
L
N
D
N
V
S
P
M
K
N
L
T
Zebra Danio
Brachydanio rerio
P79733
386
44575
E13
S
P
L
K
T
K
N
E
N
T
I
S
T
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48592
393
45096
K21
F
S
L
K
S
P
S
K
K
I
L
T
D
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42170
381
44271
N13
I
Q
N
V
E
K
E
N
A
G
A
S
V
P
K
Sea Urchin
Strong. purpuratus
XP_780110
412
47263
D26
K
M
Q
N
S
A
I
D
D
K
E
N
E
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6Y657
333
38312
Baker's Yeast
Sacchar. cerevisiae
P09938
399
46129
N25
E
I
K
D
S
K
S
N
L
N
K
E
L
E
T
Red Bread Mold
Neurospora crassa
Q9C167
410
46679
Q16
K
Q
V
T
S
G
I
Q
N
L
N
M
D
S
P
Conservation
Percent
Protein Identity:
100
N.A.
72.4
95.4
N.A.
91.2
89.7
N.A.
90.6
88.4
84
83.5
N.A.
68.9
N.A.
59.9
67.9
Protein Similarity:
100
N.A.
82
96.4
N.A.
95.3
94.6
N.A.
95.4
94
91
90.7
N.A.
79.3
N.A.
74.8
77.6
P-Site Identity:
100
N.A.
0
33.3
N.A.
73.3
66.6
N.A.
13.3
40
13.3
0
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
N.A.
0
40
N.A.
73.3
66.6
N.A.
26.6
53.3
20
20
N.A.
13.3
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.8
58.4
64.3
Protein Similarity:
N.A.
N.A.
N.A.
69.9
71.4
75.8
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
7
7
27
14
0
14
14
7
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
14
0
7
0
7
27
0
0
0
20
7
7
% D
% Glu:
7
0
0
0
14
0
7
14
7
0
7
7
7
7
0
% E
% Phe:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
7
0
0
0
7
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
14
0
0
0
0
34
0
0
7
7
0
0
0
0
% I
% Lys:
14
0
7
14
0
27
0
7
7
7
7
7
0
7
7
% K
% Leu:
0
0
20
34
0
0
0
0
7
7
7
7
47
14
34
% L
% Met:
7
7
0
0
0
0
0
0
0
0
7
7
0
0
7
% M
% Asn:
0
0
7
7
7
0
14
14
14
7
7
7
7
0
0
% N
% Pro:
0
14
27
7
7
14
7
7
7
14
14
0
0
7
14
% P
% Gln:
0
14
14
0
0
7
14
20
7
34
27
27
0
20
0
% Q
% Arg:
27
0
0
0
0
7
7
0
0
0
0
7
0
7
0
% R
% Ser:
7
7
0
0
34
0
14
0
7
0
0
20
0
20
0
% S
% Thr:
7
7
0
7
7
14
0
7
0
7
0
7
7
0
20
% T
% Val:
0
14
7
7
0
0
0
7
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _