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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM2
All Species:
7.88
Human Site:
T60
Identified Species:
12.38
UniProt:
P31350
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31350
NP_001025.1
389
44878
T60
Q
E
P
T
E
P
K
T
K
A
A
A
P
G
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100144
351
40744
Y56
Y
P
D
I
W
K
M
Y
K
Q
A
Q
A
S
F
Dog
Lupus familis
XP_540076
394
45449
T65
Q
E
P
A
E
P
K
T
K
V
L
A
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P11157
390
45077
S60
Q
D
S
A
E
L
E
S
K
A
P
T
N
P
S
Rat
Rattus norvegicus
Q4KLN6
390
45020
S60
Q
D
S
A
E
L
E
S
K
A
P
T
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506085
394
45462
V64
Q
E
P
L
E
S
V
V
S
S
W
A
S
P
R
Chicken
Gallus gallus
XP_419948
384
44421
R60
S
E
G
T
P
V
A
R
G
A
E
E
E
P
L
Frog
Xenopus laevis
NP_001080772
386
44577
R63
S
K
V
P
K
N
P
R
F
T
D
E
P
L
L
Zebra Danio
Brachydanio rerio
P79733
386
44575
K61
E
G
Q
S
K
A
K
K
G
A
V
E
E
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48592
393
45096
F69
M
E
K
S
V
T
P
F
D
P
S
L
E
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42170
381
44271
D61
E
V
N
E
L
D
A
D
E
P
M
L
Q
D
L
Sea Urchin
Strong. purpuratus
XP_780110
412
47263
E74
K
S
K
L
V
K
P
E
N
S
G
K
K
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6Y657
333
38312
F38
Y
K
K
A
E
A
S
F
W
T
A
E
E
V
D
Baker's Yeast
Sacchar. cerevisiae
P09938
399
46129
E73
R
H
K
L
K
E
M
E
K
E
E
P
L
L
N
Red Bread Mold
Neurospora crassa
Q9C167
410
46679
K64
N
K
K
A
A
E
A
K
K
M
A
P
T
L
K
Conservation
Percent
Protein Identity:
100
N.A.
72.4
95.4
N.A.
91.2
89.7
N.A.
90.6
88.4
84
83.5
N.A.
68.9
N.A.
59.9
67.9
Protein Similarity:
100
N.A.
82
96.4
N.A.
95.3
94.6
N.A.
95.4
94
91
90.7
N.A.
79.3
N.A.
74.8
77.6
P-Site Identity:
100
N.A.
13.3
66.6
N.A.
26.6
26.6
N.A.
33.3
20
6.6
13.3
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
N.A.
13.3
66.6
N.A.
46.6
46.6
N.A.
40
26.6
26.6
33.3
N.A.
26.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.8
58.4
64.3
Protein Similarity:
N.A.
N.A.
N.A.
69.9
71.4
75.8
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
7
14
20
0
0
34
27
20
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
7
0
0
7
0
7
7
0
7
0
0
7
7
% D
% Glu:
14
34
0
7
40
14
14
14
7
7
14
27
27
7
0
% E
% Phe:
0
0
0
0
0
0
0
14
7
0
0
0
0
0
7
% F
% Gly:
0
7
7
0
0
0
0
0
14
0
7
0
0
7
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
20
34
0
20
14
20
14
47
0
0
7
14
0
7
% K
% Leu:
0
0
0
20
7
14
0
0
0
0
7
14
7
20
27
% L
% Met:
7
0
0
0
0
0
14
0
0
7
7
0
0
0
0
% M
% Asn:
7
0
7
0
0
7
0
0
7
0
0
0
7
0
7
% N
% Pro:
0
7
20
7
7
14
20
0
0
14
14
14
20
34
7
% P
% Gln:
34
0
7
0
0
0
0
0
0
7
0
7
7
0
0
% Q
% Arg:
7
0
0
0
0
0
0
14
0
0
0
0
0
0
7
% R
% Ser:
14
7
14
14
0
7
7
14
7
14
7
0
7
14
14
% S
% Thr:
0
0
0
14
0
7
0
14
0
14
0
14
7
0
0
% T
% Val:
0
7
7
0
14
7
7
7
0
7
7
0
0
14
14
% V
% Trp:
0
0
0
0
7
0
0
0
7
0
7
0
0
0
0
% W
% Tyr:
14
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _