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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASQ1
All Species:
18.18
Human Site:
S265
Identified Species:
40
UniProt:
P31415
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31415
NP_001222.3
390
44498
S265
L
R
K
L
K
P
E
S
M
Y
E
T
W
E
D
Chimpanzee
Pan troglodytes
XP_001171165
390
44481
S265
L
R
K
L
K
P
E
S
M
Y
E
T
W
E
D
Rhesus Macaque
Macaca mulatta
XP_001115441
254
29420
E146
I
H
I
V
A
F
A
E
E
A
D
P
D
G
F
Dog
Lupus familis
XP_850097
395
44975
S265
L
R
K
L
K
P
E
S
M
Y
E
T
W
E
D
Cat
Felis silvestris
Mouse
Mus musculus
O09165
399
45629
S265
L
R
K
L
K
P
E
S
M
Y
E
T
W
E
D
Rat
Rattus norvegicus
P51868
413
47820
D256
L
R
P
L
R
P
E
D
M
F
E
T
W
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521326
214
24960
N106
L
K
Q
V
A
R
D
N
T
D
N
P
D
L
S
Chicken
Gallus gallus
P19204
406
47133
D256
L
R
K
L
R
P
E
D
M
F
E
T
W
E
D
Frog
Xenopus laevis
NP_001080227
428
49301
S259
L
R
K
L
K
P
D
S
M
Y
E
T
W
E
D
Zebra Danio
Brachydanio rerio
NP_001002682
409
47312
D257
L
R
K
L
K
A
E
D
M
F
E
T
W
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510438
417
48308
N265
M
Q
K
L
T
L
D
N
Y
F
N
L
W
R
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
63.5
94.6
N.A.
92.7
61
N.A.
21.2
66
70.7
62.5
N.A.
N.A.
N.A.
31.8
N.A.
Protein Similarity:
100
100
64.3
96.9
N.A.
96.2
77.4
N.A.
35.1
79.5
80.1
77.7
N.A.
N.A.
N.A.
56.3
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
73.3
N.A.
6.6
80
93.3
80
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
86.6
N.A.
40
93.3
100
86.6
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
10
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
28
28
0
10
10
0
19
0
82
% D
% Glu:
0
0
0
0
0
0
64
10
10
0
73
0
0
73
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
37
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
73
0
55
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
82
0
0
82
0
10
0
0
0
0
0
10
0
10
0
% L
% Met:
10
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
0
19
0
0
0
0
% N
% Pro:
0
0
10
0
0
64
0
0
0
0
0
19
0
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
73
0
0
19
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
46
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
0
73
0
0
0
% T
% Val:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
46
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _