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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASQ1 All Species: 23.94
Human Site: Y51 Identified Species: 52.67
UniProt: P31415 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31415 NP_001222.3 390 44498 Y51 I N V N A K N Y K N V F K K Y
Chimpanzee Pan troglodytes XP_001171165 390 44481 Y51 I N V N A K N Y K N V F K K Y
Rhesus Macaque Macaca mulatta XP_001115441 254 29420
Dog Lupus familis XP_850097 395 44975 Y51 V N V N A K N Y K N V F K K Y
Cat Felis silvestris
Mouse Mus musculus O09165 399 45629 Y51 I N V N A K N Y K N V F K K Y
Rat Rattus norvegicus P51868 413 47820 L42 V S L S E K N L K Q V L K R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521326 214 24960
Chicken Gallus gallus P19204 406 47133 Y42 I D L N E K N Y K H A L K K Y
Frog Xenopus laevis NP_001080227 428 49301 Y45 I N I N L K N Y K A A L K K Y
Zebra Danio Brachydanio rerio NP_001002682 409 47312 Y43 L D I D D K N Y R K A L K K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_510438 417 48308 F52 E V L T E K N F N R T V F A E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 63.5 94.6 N.A. 92.7 61 N.A. 21.2 66 70.7 62.5 N.A. N.A. N.A. 31.8 N.A.
Protein Similarity: 100 100 64.3 96.9 N.A. 96.2 77.4 N.A. 35.1 79.5 80.1 77.7 N.A. N.A. N.A. 56.3 N.A.
P-Site Identity: 100 100 0 93.3 N.A. 100 40 N.A. 0 60 66.6 40 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 73.3 N.A. 0 80 73.3 73.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 37 0 0 0 0 10 28 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 10 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 28 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 37 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 46 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 82 0 0 64 10 0 0 73 64 0 % K
% Leu: 10 0 28 0 10 0 0 10 0 0 0 37 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 46 0 55 0 0 82 0 10 37 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % R
% Ser: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 19 10 37 0 0 0 0 0 0 0 46 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 0 0 0 0 0 0 73 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _