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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIA1 All Species: 24.55
Human Site: S201 Identified Species: 49.09
UniProt: P31483 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31483 NP_071320.2 386 42963 S201 E S N T K Q L S Y D E V V N Q
Chimpanzee Pan troglodytes XP_001154825 563 61985 R380 E N N T K Q L R F E D V V N Q
Rhesus Macaque Macaca mulatta XP_001098789 386 42918 S201 E S N T K Q L S Y D E V V N Q
Dog Lupus familis XP_866571 386 42898 S201 E S N T K Q L S Y D E V V N Q
Cat Felis silvestris
Mouse Mus musculus P52912 386 42781 S201 E S N T K Q L S Y D E V V S Q
Rat Rattus norvegicus Q9EPH8 636 70682 E281 T E L K R K F E Q M K Q D R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514793 386 43037 S201 P K S T Q E N S T K Q L R F E
Chicken Gallus gallus XP_001233215 383 42436 N196 P K S T Y E S N T K Q L S Y D
Frog Xenopus laevis NP_001087561 389 42960 T201 E S N A K Q L T Y E E V V N Q
Zebra Danio Brachydanio rerio NP_997793 386 42278 S191 E T N T K H L S F D E V V N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42731 629 68654 E305 T E L R V R Y E Q N L K E A A
Baker's Yeast Sacchar. cerevisiae P32588 453 50771 N257 Q Q R R N Y G N N N R G G F R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.7 99.7 98.9 N.A. 96.6 20.7 N.A. 71.7 95.3 86.6 82.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 56.1 100 99.4 N.A. 98.6 32.3 N.A. 81 97.6 94.5 90.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 66.6 100 100 N.A. 93.3 0 N.A. 13.3 6.6 80 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 20 N.A. 53.3 40 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.7 20 N.A.
Protein Similarity: N.A. N.A. N.A. 36.4 37.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 42 9 0 9 0 9 % D
% Glu: 59 17 0 0 0 17 0 17 0 17 50 0 9 0 9 % E
% Phe: 0 0 0 0 0 0 9 0 17 0 0 0 0 17 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 9 9 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 17 0 9 59 9 0 0 0 17 9 9 0 0 0 % K
% Leu: 0 0 17 0 0 0 59 0 0 0 9 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 9 59 0 9 0 9 17 9 17 0 0 0 50 0 % N
% Pro: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 9 0 0 9 50 0 0 17 0 17 9 0 0 59 % Q
% Arg: 0 0 9 17 9 9 0 9 0 0 9 0 9 9 9 % R
% Ser: 0 42 17 0 0 0 9 50 0 0 0 0 9 9 0 % S
% Thr: 17 9 0 67 0 0 0 9 17 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 59 59 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 9 9 0 42 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _