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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIA1
All Species:
18.18
Human Site:
Y251
Identified Species:
36.36
UniProt:
P31483
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31483
NP_071320.2
386
42963
Y251
R
V
F
P
D
K
G
Y
S
F
V
R
F
N
S
Chimpanzee
Pan troglodytes
XP_001154825
563
61985
G429
I
R
V
F
P
E
K
G
Y
S
F
V
R
F
S
Rhesus Macaque
Macaca mulatta
XP_001098789
386
42918
Y251
R
V
F
P
D
K
G
Y
S
F
V
R
F
N
S
Dog
Lupus familis
XP_866571
386
42898
Y251
R
V
F
P
D
K
G
Y
S
F
V
R
F
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P52912
386
42781
Y251
R
V
F
P
D
K
G
Y
S
F
V
R
F
S
S
Rat
Rattus norvegicus
Q9EPH8
636
70682
F335
E
G
G
R
S
K
G
F
G
F
V
C
F
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514793
386
43037
P252
I
M
E
I
R
V
F
P
E
K
G
Y
S
F
V
Chicken
Gallus gallus
XP_001233215
383
42436
K249
E
I
R
V
F
P
D
K
G
Y
S
F
V
R
F
Frog
Xenopus laevis
NP_001087561
389
42960
V254
P
D
K
G
Y
S
F
V
R
F
S
S
H
E
S
Zebra Danio
Brachydanio rerio
NP_997793
386
42278
Y241
R
V
F
P
D
K
G
Y
S
F
V
R
F
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42731
629
68654
F407
R
V
R
L
Q
A
Q
F
S
Q
V
R
P
V
A
Baker's Yeast
Sacchar. cerevisiae
P32588
453
50771
I318
Q
P
Q
Q
S
Q
T
I
G
L
P
P
Q
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.7
99.7
98.9
N.A.
96.6
20.7
N.A.
71.7
95.3
86.6
82.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.1
100
99.4
N.A.
98.6
32.3
N.A.
81
97.6
94.5
90.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
40
N.A.
0
0
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
53.3
N.A.
6.6
13.3
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.4
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
0
0
42
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
17
0
9
0
0
9
0
0
9
0
0
0
0
9
0
% E
% Phe:
0
0
42
9
9
0
17
17
0
59
9
9
50
17
9
% F
% Gly:
0
9
9
9
0
0
50
9
25
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
17
9
0
9
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
50
9
9
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
9
% N
% Pro:
9
9
0
42
9
9
0
9
0
0
9
9
9
0
0
% P
% Gln:
9
0
9
9
9
9
9
0
0
9
0
0
9
0
0
% Q
% Arg:
50
9
17
9
9
0
0
0
9
0
0
50
9
9
0
% R
% Ser:
0
0
0
0
17
9
0
0
50
9
17
9
9
17
67
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
50
9
9
0
9
0
9
0
0
59
9
9
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
42
9
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _