KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIVEP2
All Species:
11.82
Human Site:
T1249
Identified Species:
32.5
UniProt:
P31629
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31629
NP_006725.3
2446
269053
T1249
Y
G
K
P
S
F
Q
T
E
I
H
S
S
Y
P
Chimpanzee
Pan troglodytes
XP_518773
2611
286870
T1414
Y
G
K
P
S
F
Q
T
E
I
H
S
S
Y
P
Rhesus Macaque
Macaca mulatta
XP_001092694
2411
264713
T1214
Y
G
K
P
S
F
Q
T
E
I
H
S
S
Y
P
Dog
Lupus familis
XP_850296
2435
267534
A1244
Y
G
K
P
S
F
Q
A
E
I
H
P
G
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHF7
2430
266686
A1237
Y
S
K
P
P
F
Q
A
D
L
H
S
S
Y
P
Rat
Rattus norvegicus
Q00900
2437
267408
D1244
S
K
P
P
F
Q
A
D
I
H
S
S
Y
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507497
2629
288405
P1431
Y
V
R
S
P
F
Q
P
E
L
H
T
G
Y
H
Chicken
Gallus gallus
XP_419711
2470
273534
T1268
Y
V
K
Q
P
F
Q
T
D
I
P
P
S
Y
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025335
2298
253367
I1169
P
Y
Q
P
S
H
Q
I
Q
V
Q
T
D
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
93.3
91.9
N.A.
87.2
87.5
N.A.
74
73.8
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.4
93.9
94.4
N.A.
92
92
N.A.
79.9
82.4
N.A.
59.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
66.6
13.3
N.A.
40
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
13.3
N.A.
60
60
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
23
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
23
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
56
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
78
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
45
0
0
0
0
0
0
0
0
0
0
23
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
12
67
0
0
0
23
% H
% Ile:
0
0
0
0
0
0
0
12
12
56
0
0
0
0
0
% I
% Lys:
0
12
67
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
12
78
34
0
0
12
0
0
12
23
0
0
56
% P
% Gln:
0
0
12
12
0
12
89
0
12
0
12
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
12
0
12
56
0
0
0
0
0
12
56
56
23
0
% S
% Thr:
0
0
0
0
0
0
0
45
0
0
0
23
0
0
0
% T
% Val:
0
23
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
78
12
0
0
0
0
0
0
0
0
0
0
12
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _