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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL2RG
All Species:
10.61
Human Site:
Y325
Identified Species:
29.17
UniProt:
P31785
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31785
NP_000197.1
369
42287
Y325
A
E
S
L
Q
P
D
Y
S
E
R
L
C
L
V
Chimpanzee
Pan troglodytes
XP_521112
465
54141
S353
S
K
Y
L
T
A
R
S
T
Y
Y
V
C
K
V
Rhesus Macaque
Macaca mulatta
NP_001030606
369
42308
Y325
A
E
S
L
Q
P
D
Y
S
E
R
L
C
L
V
Dog
Lupus familis
XP_851588
495
56165
D384
H
V
K
D
K
W
N
D
N
Q
P
S
D
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
P34902
369
42223
S326
E
S
L
Q
P
D
Y
S
E
R
F
C
H
V
S
Rat
Rattus norvegicus
NP_543165
368
42378
S325
E
S
L
Q
P
D
Y
S
E
R
F
C
H
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989858
374
42529
Y329
V
E
S
F
K
P
N
Y
S
E
S
I
C
H
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121743
362
41194
D316
I
F
S
Q
S
S
S
D
S
E
S
I
L
S
N
Tiger Blowfish
Takifugu rubipres
NP_001129354
315
36204
P273
L
L
P
V
V
P
K
P
S
F
S
S
Y
D
I
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.8
97.2
20.8
N.A.
70.7
74.2
N.A.
N.A.
39.2
N.A.
28.4
23.3
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
66.8
98
36.7
N.A.
81.5
85
N.A.
N.A.
55
N.A.
46
36.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
0
N.A.
0
0
N.A.
N.A.
53.3
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
26.6
N.A.
6.6
6.6
N.A.
N.A.
73.3
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
23
45
0
0
% C
% Asp:
0
0
0
12
0
23
23
23
0
0
0
0
12
12
0
% D
% Glu:
23
34
0
0
0
0
0
0
23
45
0
0
0
0
0
% E
% Phe:
0
12
0
12
0
0
0
0
0
12
23
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
23
23
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
23
0
0
12
% I
% Lys:
0
12
12
0
23
0
12
0
0
0
0
0
0
12
0
% K
% Leu:
12
12
23
34
0
0
0
0
0
0
0
23
12
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
23
0
12
0
0
0
0
0
12
% N
% Pro:
0
0
12
0
23
45
0
12
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
34
23
0
0
0
0
12
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
0
12
0
0
23
23
0
0
0
0
% R
% Ser:
12
23
45
0
12
12
12
34
56
0
34
23
0
12
23
% S
% Thr:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% T
% Val:
12
12
0
12
12
0
0
0
0
0
0
12
0
23
45
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
23
34
0
12
12
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _