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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATIC
All Species:
37.88
Human Site:
S167
Identified Species:
75.76
UniProt:
P31939
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31939
NP_004035.2
592
64616
S167
S
S
E
S
K
D
T
S
L
E
T
R
R
Q
L
Chimpanzee
Pan troglodytes
XP_001150375
592
64537
S167
S
S
E
S
K
D
T
S
L
E
T
R
R
Q
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545634
592
64708
S167
S
S
D
S
K
D
T
S
L
E
T
R
R
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWJ9
592
64199
S167
G
S
D
S
K
D
T
S
L
E
T
R
R
H
L
Rat
Rattus norvegicus
O35567
592
64190
S167
G
S
G
N
K
D
T
S
L
E
T
R
R
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P31335
593
64396
S168
A
S
K
D
K
D
T
S
V
E
T
R
R
H
L
Frog
Xenopus laevis
NP_001090100
589
63809
S165
N
S
D
N
K
D
T
S
P
E
T
R
C
R
L
Zebra Danio
Brachydanio rerio
NP_001076265
590
64026
T166
T
S
E
I
H
D
T
T
M
E
T
R
K
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651305
590
63305
T165
L
K
A
S
G
N
T
T
V
E
T
R
Q
A
L
Honey Bee
Apis mellifera
XP_395924
593
65708
S167
S
S
I
N
K
D
T
S
L
E
T
R
Q
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793444
592
64337
T167
E
R
P
D
N
D
T
T
I
E
S
R
K
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38009
592
65245
D168
S
N
G
E
I
S
Q
D
L
R
N
R
L
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
94.7
N.A.
91
91.2
N.A.
N.A.
83.4
77.5
79.3
N.A.
70.6
68.8
N.A.
68.7
Protein Similarity:
100
99.8
N.A.
98.1
N.A.
95.7
95.6
N.A.
N.A.
92.9
92.2
89.8
N.A.
83.2
81.4
N.A.
81.7
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
73.3
N.A.
N.A.
66.6
60
53.3
N.A.
40
73.3
N.A.
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
80
N.A.
N.A.
86.6
86.6
80
N.A.
66.6
86.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
61.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
76.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
25
17
0
84
0
9
0
0
0
0
0
0
0
% D
% Glu:
9
0
25
9
0
0
0
0
0
92
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
17
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
25
0
% H
% Ile:
0
0
9
9
9
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
67
0
0
0
0
0
0
0
17
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
59
0
0
0
9
9
100
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
9
0
25
9
9
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
17
25
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
9
0
100
50
9
0
% R
% Ser:
42
75
0
42
0
9
0
67
0
0
9
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
92
25
0
0
84
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _