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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFN
All Species:
37.27
Human Site:
S186
Identified Species:
68.33
UniProt:
P31947
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31947
NP_006133.1
248
27774
S186
F
H
Y
E
I
A
N
S
P
E
E
A
I
S
L
Chimpanzee
Pan troglodytes
XP_528202
382
42115
S321
F
Y
Y
E
I
L
N
S
P
E
K
A
C
S
L
Rhesus Macaque
Macaca mulatta
XP_001110323
248
27784
S186
F
H
Y
E
I
A
N
S
P
E
E
A
I
S
L
Dog
Lupus familis
XP_544477
248
27815
S186
F
H
Y
E
I
A
N
S
P
E
E
A
I
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O70456
248
27695
S186
F
H
Y
E
I
A
N
S
P
E
E
A
I
S
L
Rat
Rattus norvegicus
P63102
245
27753
S184
F
Y
Y
E
I
L
N
S
P
E
K
A
C
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511520
248
27538
S186
F
H
Y
E
I
A
N
S
P
E
E
A
I
S
L
Chicken
Gallus gallus
Q5ZMD1
245
27764
N184
F
Y
Y
E
I
L
N
N
P
E
L
A
C
T
L
Frog
Xenopus laevis
Q5XHK2
244
27740
S184
F
Y
Y
E
I
L
N
S
P
E
K
A
C
S
L
Zebra Danio
Brachydanio rerio
Q7T356
242
27374
N183
V
F
Y
Y
E
I
L
N
S
P
E
N
A
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
S187
F
Y
Y
E
I
L
N
S
P
D
K
A
C
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
A186
F
F
Y
E
I
L
N
A
P
D
K
A
C
Q
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q01525
259
29143
S190
F
Y
Y
E
I
L
N
S
P
D
R
A
C
N
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
99.5
97.9
N.A.
96.3
69.7
N.A.
90.7
68.5
66.5
68.9
N.A.
64.9
N.A.
64.5
N.A.
Protein Similarity:
100
54.4
100
98.7
N.A.
97.9
83
N.A.
93.9
84.6
81.4
82.6
N.A.
79.8
N.A.
79.8
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
100
73.3
N.A.
100
60
73.3
13.3
N.A.
60
N.A.
53.3
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
86.6
N.A.
100
80
86.6
20
N.A.
80
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
39
0
8
0
0
0
93
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
54
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% D
% Glu:
0
0
0
93
8
0
0
0
0
70
47
0
0
0
0
% E
% Phe:
93
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
93
8
0
0
0
0
0
0
39
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% K
% Leu:
0
0
0
0
0
54
8
0
0
0
8
0
0
0
93
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
93
16
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
93
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
77
8
0
0
0
0
62
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
47
100
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _