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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFN
All Species:
9.09
Human Site:
S69
Identified Species:
16.67
UniProt:
P31947
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31947
NP_006133.1
248
27774
S69
L
S
S
I
E
Q
K
S
N
E
E
G
S
E
E
Chimpanzee
Pan troglodytes
XP_528202
382
42115
Q204
R
V
V
S
S
I
E
Q
K
T
E
G
A
E
K
Rhesus Macaque
Macaca mulatta
XP_001110323
248
27784
S69
L
S
S
I
E
Q
K
S
N
E
E
G
S
E
E
Dog
Lupus familis
XP_544477
248
27815
G69
L
S
S
I
E
Q
K
G
N
E
E
S
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
O70456
248
27695
S69
L
S
S
I
E
Q
K
S
N
E
E
G
S
E
E
Rat
Rattus norvegicus
P63102
245
27753
Q67
R
V
V
S
S
I
E
Q
K
T
E
G
A
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511520
248
27538
G69
L
S
S
I
E
H
K
G
P
E
E
G
G
E
E
Chicken
Gallus gallus
Q5ZMD1
245
27764
Q67
R
V
I
S
S
I
E
Q
K
T
D
T
S
D
K
Frog
Xenopus laevis
Q5XHK2
244
27740
Q67
R
V
I
S
S
I
E
Q
K
T
E
G
N
D
K
Zebra Danio
Brachydanio rerio
Q7T356
242
27374
E66
W
R
V
I
S
S
I
E
Q
K
T
E
G
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
Q70
R
V
I
S
S
I
E
Q
K
T
E
A
S
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
Q69
R
V
I
S
S
I
E
Q
K
T
E
G
S
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q01525
259
29143
E73
I
S
S
I
E
Q
K
E
E
S
R
G
N
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
99.5
97.9
N.A.
96.3
69.7
N.A.
90.7
68.5
66.5
68.9
N.A.
64.9
N.A.
64.5
N.A.
Protein Similarity:
100
54.4
100
98.7
N.A.
97.9
83
N.A.
93.9
84.6
81.4
82.6
N.A.
79.8
N.A.
79.8
N.A.
P-Site Identity:
100
20
100
86.6
N.A.
100
20
N.A.
73.3
6.6
13.3
13.3
N.A.
13.3
N.A.
26.6
N.A.
P-Site Similarity:
100
40
100
86.6
N.A.
100
40
N.A.
73.3
33.3
40
20
N.A.
20
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
24
8
% D
% Glu:
0
0
0
0
47
0
47
16
8
39
77
8
0
62
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
0
0
0
70
16
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
31
54
0
47
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
47
0
47
8
0
0
0
0
39
% K
% Leu:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
31
0
0
0
16
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
39
0
47
8
0
0
0
0
0
0
% Q
% Arg:
47
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% R
% Ser:
0
47
47
47
54
8
0
24
0
8
0
8
54
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
47
8
8
0
0
0
% T
% Val:
0
47
24
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _