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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFN All Species: 17.88
Human Site: T98 Identified Species: 32.78
UniProt: P31947 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31947 NP_006133.1 248 27774 T98 E L Q G V C D T V L G L L D S
Chimpanzee Pan troglodytes XP_528202 382 42115 D233 E L R D I C N D V L S L L E K
Rhesus Macaque Macaca mulatta XP_001110323 248 27784 T98 E L R G V C D T V L G L L D S
Dog Lupus familis XP_544477 248 27815 T98 E L R G V C D T V L G L L D S
Cat Felis silvestris
Mouse Mus musculus O70456 248 27695 T98 E L R G V C D T V L G L L D S
Rat Rattus norvegicus P63102 245 27753 D96 E L R D I C N D V L S L L E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511520 248 27538 A98 E L R A V C G A V L A L L D S
Chicken Gallus gallus Q5ZMD1 245 27764 T96 E L R S I C T T V L E L L D K
Frog Xenopus laevis Q5XHK2 244 27740 D96 E L Q D I C K D V L D L L D R
Zebra Danio Brachydanio rerio Q7T356 242 27374 S95 T E L Q D I C S D V L G L L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29310 248 28209 E99 E L R E I C Y E V L G L L D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20655 248 28049 D98 E L R D I C Q D V L N L L D K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q01525 259 29143 G102 E L S G I C D G I L K L L D S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 99.5 97.9 N.A. 96.3 69.7 N.A. 90.7 68.5 66.5 68.9 N.A. 64.9 N.A. 64.5 N.A.
Protein Similarity: 100 54.4 100 98.7 N.A. 97.9 83 N.A. 93.9 84.6 81.4 82.6 N.A. 79.8 N.A. 79.8 N.A.
P-Site Identity: 100 46.6 93.3 93.3 N.A. 93.3 46.6 N.A. 66.6 60 60 6.6 N.A. 60 N.A. 53.3 N.A.
P-Site Similarity: 100 73.3 100 100 N.A. 100 73.3 N.A. 73.3 73.3 66.6 20 N.A. 73.3 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 58.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 72.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 80 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 93 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 31 8 0 39 31 8 0 8 0 0 77 0 % D
% Glu: 93 8 0 8 0 0 0 8 0 0 8 0 0 16 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 39 0 0 8 8 0 0 39 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 54 8 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 39 % K
% Leu: 0 93 8 0 0 0 0 0 0 93 8 93 100 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 16 8 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 70 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 8 8 0 0 0 8 0 0 16 0 0 0 47 % S
% Thr: 8 0 0 0 0 0 8 39 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 39 0 0 0 85 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _