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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFN
All Species:
40.61
Human Site:
Y84
Identified Species:
74.44
UniProt:
P31947
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31947
NP_006133.1
248
27774
Y84
K
G
P
E
V
R
E
Y
R
E
K
V
E
T
E
Chimpanzee
Pan troglodytes
XP_528202
382
42115
Y219
K
Q
Q
M
A
R
E
Y
R
E
K
I
E
T
E
Rhesus Macaque
Macaca mulatta
XP_001110323
248
27784
Y84
K
G
P
E
V
R
E
Y
R
E
K
V
E
T
E
Dog
Lupus familis
XP_544477
248
27815
Y84
K
G
P
E
V
R
E
Y
R
E
K
V
E
T
E
Cat
Felis silvestris
Mouse
Mus musculus
O70456
248
27695
Y84
K
G
P
E
V
K
E
Y
R
E
K
V
E
T
E
Rat
Rattus norvegicus
P63102
245
27753
Y82
K
Q
Q
M
A
R
E
Y
R
E
K
I
E
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511520
248
27538
Y84
R
G
P
E
V
R
D
Y
R
E
K
V
E
G
E
Chicken
Gallus gallus
Q5ZMD1
245
27764
Y82
K
M
Q
L
I
K
D
Y
R
E
K
V
E
S
E
Frog
Xenopus laevis
Q5XHK2
244
27740
Y82
R
Q
Q
M
A
R
E
Y
R
E
K
V
E
T
E
Zebra Danio
Brachydanio rerio
Q7T356
242
27374
E81
K
K
Q
Q
M
A
R
E
Y
R
E
K
I
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
Y85
K
Q
Q
L
A
R
E
Y
R
E
R
V
E
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
Y84
K
Q
Q
M
A
K
E
Y
R
E
K
V
E
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q01525
259
29143
Y88
H
V
T
A
I
R
E
Y
R
S
K
I
E
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
99.5
97.9
N.A.
96.3
69.7
N.A.
90.7
68.5
66.5
68.9
N.A.
64.9
N.A.
64.5
N.A.
Protein Similarity:
100
54.4
100
98.7
N.A.
97.9
83
N.A.
93.9
84.6
81.4
82.6
N.A.
79.8
N.A.
79.8
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
93.3
66.6
N.A.
80
53.3
66.6
6.6
N.A.
60
N.A.
60
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
73.3
N.A.
93.3
80
73.3
26.6
N.A.
66.6
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
39
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
39
0
0
77
8
0
85
8
0
93
8
93
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
39
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
0
0
0
0
0
0
24
8
0
0
% I
% Lys:
77
8
0
0
0
24
0
0
0
0
85
8
0
16
0
% K
% Leu:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
31
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
39
54
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
0
70
8
0
93
8
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
62
8
% T
% Val:
0
8
0
0
39
0
0
0
0
0
0
70
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _