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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5B
All Species:
0.91
Human Site:
S182
Identified Species:
1.82
UniProt:
P32019
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32019
NP_005531.2
993
112852
S182
I
G
G
G
R
Y
P
S
R
K
K
R
W
G
L
Chimpanzee
Pan troglodytes
XP_513330
1149
128671
A287
E
H
G
G
Q
E
H
A
L
F
L
Y
T
H
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549244
894
103439
S134
P
E
Q
K
D
S
S
S
W
Y
Q
K
L
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHC4
1574
172599
N217
E
R
A
G
T
R
F
N
V
R
G
T
N
D
D
Rat
Rattus norvegicus
Q62910
1574
172862
N217
E
R
A
G
T
R
F
N
V
R
G
T
N
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517168
864
99967
N104
P
P
V
D
K
P
L
N
E
S
T
A
P
G
I
Chicken
Gallus gallus
XP_417756
748
85320
Frog
Xenopus laevis
Q6P4S2
1019
115278
Q202
T
G
S
Q
T
L
P
Q
F
K
K
L
L
M
T
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
Q235
M
V
S
R
M
I
Q
Q
S
M
S
Q
G
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569962
850
97512
A89
L
I
I
N
K
V
F
A
I
D
H
N
F
Q
L
Honey Bee
Apis mellifera
XP_396184
846
96645
Q86
I
N
T
D
D
K
Q
Q
D
S
L
D
V
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797066
1060
119256
A191
T
N
P
F
M
S
H
A
K
T
M
P
L
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
N.A.
44
N.A.
21.7
22.2
N.A.
43.9
58.3
20
20.5
N.A.
28.2
38.5
N.A.
36.1
Protein Similarity:
100
74.5
N.A.
62
N.A.
36.8
37
N.A.
61
65.4
36
36.5
N.A.
47.1
55.6
N.A.
52.8
P-Site Identity:
100
13.3
N.A.
6.6
N.A.
6.6
6.6
N.A.
6.6
0
26.6
6.6
N.A.
6.6
13.3
N.A.
0
P-Site Similarity:
100
26.6
N.A.
20
N.A.
20
20
N.A.
26.6
0
26.6
20
N.A.
33.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
25
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
17
0
0
0
9
9
0
9
0
25
34
% D
% Glu:
25
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
25
0
9
9
0
0
9
0
0
% F
% Gly:
0
17
17
34
0
0
0
0
0
0
17
0
9
25
0
% G
% His:
0
9
0
0
0
0
17
0
0
0
9
0
0
9
0
% H
% Ile:
17
9
9
0
0
9
0
0
9
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
17
9
0
0
9
17
17
9
0
0
0
% K
% Leu:
9
0
0
0
0
9
9
0
9
0
17
9
25
9
25
% L
% Met:
9
0
0
0
17
0
0
0
0
9
9
0
0
9
0
% M
% Asn:
0
17
0
9
0
0
0
25
0
0
0
9
17
0
0
% N
% Pro:
17
9
9
0
0
9
17
0
0
0
0
9
9
0
0
% P
% Gln:
0
0
9
9
9
0
17
25
0
0
9
9
0
9
0
% Q
% Arg:
0
17
0
9
9
17
0
0
9
17
0
9
0
0
9
% R
% Ser:
0
0
17
0
0
17
9
17
9
17
9
0
0
0
0
% S
% Thr:
17
0
9
0
25
0
0
0
0
9
9
17
9
0
17
% T
% Val:
0
9
9
0
0
9
0
0
17
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
9
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _