KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5B
All Species:
3.94
Human Site:
S246
Identified Species:
7.88
UniProt:
P32019
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32019
NP_005531.2
993
112852
S246
E
E
A
G
R
E
M
S
A
A
A
G
S
R
E
Chimpanzee
Pan troglodytes
XP_513330
1149
128671
L402
P
R
G
C
N
S
A
L
V
T
W
P
G
Y
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549244
894
103439
L190
P
P
S
V
N
R
M
L
P
R
D
K
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHC4
1574
172599
N432
F
R
S
M
W
S
V
N
G
D
S
I
S
K
I
Rat
Rattus norvegicus
Q62910
1574
172862
N432
F
R
S
M
W
S
V
N
G
D
S
I
S
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517168
864
99967
E160
E
R
E
A
T
S
K
E
Q
P
K
V
T
N
T
Chicken
Gallus gallus
XP_417756
748
85320
K44
R
S
A
P
R
Q
S
K
L
K
P
E
V
T
T
Frog
Xenopus laevis
Q6P4S2
1019
115278
P291
K
H
R
R
S
L
I
P
P
I
I
F
E
V
K
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
T308
D
V
Y
L
A
D
L
T
K
I
G
K
S
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569962
850
97512
A146
I
S
F
K
S
T
M
A
Q
H
D
P
E
T
V
Honey Bee
Apis mellifera
XP_396184
846
96645
N142
R
N
L
N
S
N
T
N
E
E
V
Q
D
N
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797066
1060
119256
S292
S
S
S
S
S
S
S
S
S
S
T
S
S
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
N.A.
44
N.A.
21.7
22.2
N.A.
43.9
58.3
20
20.5
N.A.
28.2
38.5
N.A.
36.1
Protein Similarity:
100
74.5
N.A.
62
N.A.
36.8
37
N.A.
61
65.4
36
36.5
N.A.
47.1
55.6
N.A.
52.8
P-Site Identity:
100
0
N.A.
6.6
N.A.
6.6
6.6
N.A.
6.6
13.3
0
6.6
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
0
N.A.
13.3
N.A.
40
40
N.A.
13.3
20
20
46.6
N.A.
13.3
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
9
0
9
9
9
9
9
0
0
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
17
17
0
9
0
9
% D
% Glu:
17
9
9
0
0
9
0
9
9
9
0
9
25
0
9
% E
% Phe:
17
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
9
9
0
0
0
0
17
0
9
9
9
9
0
% G
% His:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
0
0
17
9
17
0
0
17
% I
% Lys:
9
0
0
9
0
0
9
9
9
9
9
17
0
17
17
% K
% Leu:
0
0
9
9
0
9
9
17
9
0
0
0
0
0
0
% L
% Met:
0
0
0
17
0
0
25
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
17
9
0
25
0
0
0
0
0
17
0
% N
% Pro:
17
9
0
9
0
0
0
9
17
9
9
17
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
17
0
0
9
0
9
0
% Q
% Arg:
17
34
9
9
17
9
0
0
0
9
0
0
0
9
0
% R
% Ser:
9
25
34
9
34
42
17
17
9
9
17
9
42
0
9
% S
% Thr:
0
0
0
0
9
9
9
9
0
9
9
0
9
17
25
% T
% Val:
0
9
0
9
0
0
17
0
9
0
9
9
9
17
9
% V
% Trp:
0
0
0
0
17
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _