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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5B
All Species:
6.67
Human Site:
S286
Identified Species:
13.33
UniProt:
P32019
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32019
NP_005531.2
993
112852
S286
R
G
Q
D
K
P
E
S
L
Q
P
R
Q
N
K
Chimpanzee
Pan troglodytes
XP_513330
1149
128671
S442
R
G
Q
D
K
L
E
S
L
Q
P
R
Q
N
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549244
894
103439
I228
R
E
G
L
I
K
H
I
L
A
K
R
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHC4
1574
172599
A495
D
L
A
D
K
A
R
A
L
L
T
T
G
S
L
Rat
Rattus norvegicus
Q62910
1574
172862
A495
D
L
A
D
K
A
R
A
L
L
T
T
G
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517168
864
99967
N198
K
R
E
K
E
Y
V
N
I
Q
N
F
R
F
F
Chicken
Gallus gallus
XP_417756
748
85320
S82
L
R
D
T
I
V
K
S
Q
L
V
Q
R
E
D
Frog
Xenopus laevis
Q6P4S2
1019
115278
L339
F
Y
P
S
K
K
I
L
Q
L
I
K
S
Q
K
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
R349
T
F
T
H
D
K
I
R
Q
L
I
K
S
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569962
850
97512
D184
S
E
Y
I
V
Y
K
D
I
I
I
Y
C
A
T
Honey Bee
Apis mellifera
XP_396184
846
96645
A180
P
V
A
A
R
E
S
A
V
R
Y
Q
M
A
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797066
1060
119256
T341
Q
Q
D
A
R
G
S
T
F
Y
T
N
L
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
N.A.
44
N.A.
21.7
22.2
N.A.
43.9
58.3
20
20.5
N.A.
28.2
38.5
N.A.
36.1
Protein Similarity:
100
74.5
N.A.
62
N.A.
36.8
37
N.A.
61
65.4
36
36.5
N.A.
47.1
55.6
N.A.
52.8
P-Site Identity:
100
93.3
N.A.
20
N.A.
20
20
N.A.
6.6
6.6
13.3
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
93.3
N.A.
33.3
N.A.
33.3
33.3
N.A.
46.6
26.6
20
13.3
N.A.
13.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
17
0
17
0
25
0
9
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% C
% Asp:
17
0
17
34
9
0
0
9
0
0
0
0
0
9
9
% D
% Glu:
0
17
9
0
9
9
17
0
0
0
0
0
9
9
9
% E
% Phe:
9
9
0
0
0
0
0
0
9
0
0
9
0
9
9
% F
% Gly:
0
17
9
0
0
9
0
0
0
0
0
0
17
0
9
% G
% His:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
17
0
17
9
17
9
25
0
0
0
0
% I
% Lys:
9
0
0
9
42
25
17
0
0
0
9
17
0
9
25
% K
% Leu:
9
17
0
9
0
9
0
9
42
42
0
0
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
9
0
17
0
% N
% Pro:
9
0
9
0
0
9
0
0
0
0
17
0
0
0
0
% P
% Gln:
9
9
17
0
0
0
0
0
25
25
0
17
17
17
0
% Q
% Arg:
25
17
0
0
17
0
17
9
0
9
0
25
17
0
9
% R
% Ser:
9
0
0
9
0
0
17
25
0
0
0
0
17
17
0
% S
% Thr:
9
0
9
9
0
0
0
9
0
0
25
17
0
0
9
% T
% Val:
0
9
0
0
9
9
9
0
9
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
0
17
0
0
0
9
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _