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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5B
All Species:
7.58
Human Site:
S305
Identified Species:
15.15
UniProt:
P32019
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32019
NP_005531.2
993
112852
S305
I
T
D
M
V
R
S
S
T
I
T
V
S
D
K
Chimpanzee
Pan troglodytes
XP_513330
1149
128671
S461
I
T
D
M
V
R
S
S
T
I
T
V
S
D
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549244
894
103439
G247
Q
T
F
R
F
F
V
G
T
W
N
V
N
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHC4
1574
172599
S514
Q
T
L
Q
S
A
S
S
K
V
L
K
N
M
C
Rat
Rattus norvegicus
Q62910
1574
172862
S514
Q
T
L
Q
S
A
S
S
K
V
L
K
N
M
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517168
864
99967
D217
N
V
N
G
Q
S
P
D
S
G
L
E
P
W
L
Chicken
Gallus gallus
XP_417756
748
85320
V101
I
Q
N
F
R
F
F
V
G
T
Y
N
V
N
G
Frog
Xenopus laevis
Q6P4S2
1019
115278
E358
L
V
I
V
L
E
T
E
K
E
K
T
Q
R
K
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
E368
L
G
I
V
F
E
K
E
K
D
K
S
Q
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569962
850
97512
N203
N
K
T
C
S
D
S
N
N
P
L
R
A
W
L
Honey Bee
Apis mellifera
XP_396184
846
96645
R199
Y
T
Y
S
K
T
F
R
I
F
I
G
T
W
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797066
1060
119256
M360
A
E
P
R
T
S
L
M
G
S
Q
P
D
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
N.A.
44
N.A.
21.7
22.2
N.A.
43.9
58.3
20
20.5
N.A.
28.2
38.5
N.A.
36.1
Protein Similarity:
100
74.5
N.A.
62
N.A.
36.8
37
N.A.
61
65.4
36
36.5
N.A.
47.1
55.6
N.A.
52.8
P-Site Identity:
100
100
N.A.
20
N.A.
20
20
N.A.
0
6.6
6.6
6.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
N.A.
33.3
N.A.
33.3
33.3
N.A.
13.3
20
33.3
20
N.A.
20
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
17
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
17
% C
% Asp:
0
0
17
0
0
9
0
9
0
9
0
0
9
17
9
% D
% Glu:
0
9
0
0
0
17
0
17
0
9
0
9
0
0
0
% E
% Phe:
0
0
9
9
17
17
17
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
9
0
0
0
9
17
9
0
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
0
17
0
0
0
0
0
9
17
9
0
0
9
0
% I
% Lys:
0
9
0
0
9
0
9
0
34
0
17
17
0
0
34
% K
% Leu:
17
0
17
0
9
0
9
0
0
0
34
0
0
0
17
% L
% Met:
0
0
0
17
0
0
0
9
0
0
0
0
0
17
0
% M
% Asn:
17
0
17
0
0
0
0
9
9
0
9
9
25
9
9
% N
% Pro:
0
0
9
0
0
0
9
0
0
9
0
9
9
0
0
% P
% Gln:
25
9
0
17
9
0
0
0
0
0
9
0
17
0
9
% Q
% Arg:
0
0
0
17
9
17
0
9
0
0
0
9
0
17
0
% R
% Ser:
0
0
0
9
25
17
42
34
9
9
0
9
17
0
0
% S
% Thr:
0
50
9
0
9
9
9
0
25
9
17
9
9
0
0
% T
% Val:
0
17
0
17
17
0
9
9
0
17
0
25
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
25
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _