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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5B
All Species:
8.79
Human Site:
S387
Identified Species:
17.58
UniProt:
P32019
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32019
NP_005531.2
993
112852
S387
G
F
Q
E
L
D
L
S
K
E
A
F
F
F
H
Chimpanzee
Pan troglodytes
XP_513330
1149
128671
S543
G
F
Q
E
L
D
L
S
K
E
A
F
F
F
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549244
894
103439
F329
V
G
M
M
L
L
I
F
A
R
K
D
Q
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHC4
1574
172599
N596
F
E
E
M
V
E
L
N
A
G
N
I
V
N
A
Rat
Rattus norvegicus
Q62910
1574
172862
N596
F
E
E
M
V
E
L
N
A
G
N
I
V
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517168
864
99967
R299
K
D
Q
L
S
H
I
R
D
I
A
A
E
T
V
Chicken
Gallus gallus
XP_417756
748
85320
L183
L
V
G
I
M
L
L
L
Y
V
K
A
D
L
A
Frog
Xenopus laevis
Q6P4S2
1019
115278
I440
A
D
Y
I
E
H
D
I
Y
V
I
G
T
Q
E
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
I450
A
V
T
I
P
H
D
I
Y
V
F
G
T
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569962
850
97512
H285
V
R
K
Q
L
R
Q
H
I
I
R
C
R
P
K
Honey Bee
Apis mellifera
XP_396184
846
96645
M281
A
I
V
R
L
V
G
M
M
L
L
I
Y
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797066
1060
119256
S442
G
F
Q
E
L
D
L
S
K
E
A
F
L
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
N.A.
44
N.A.
21.7
22.2
N.A.
43.9
58.3
20
20.5
N.A.
28.2
38.5
N.A.
36.1
Protein Similarity:
100
74.5
N.A.
62
N.A.
36.8
37
N.A.
61
65.4
36
36.5
N.A.
47.1
55.6
N.A.
52.8
P-Site Identity:
100
100
N.A.
6.6
N.A.
6.6
6.6
N.A.
13.3
6.6
0
0
N.A.
6.6
6.6
N.A.
86.6
P-Site Similarity:
100
100
N.A.
20
N.A.
33.3
33.3
N.A.
20
13.3
0
0
N.A.
20
13.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
25
0
34
17
0
9
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
17
0
0
0
25
17
0
9
0
0
9
9
0
0
% D
% Glu:
0
17
17
25
9
17
0
0
0
25
0
0
9
0
17
% E
% Phe:
17
25
0
0
0
0
0
9
0
0
9
25
17
25
0
% F
% Gly:
25
9
9
0
0
0
9
0
0
17
0
17
0
0
0
% G
% His:
0
0
0
0
0
25
0
9
0
0
0
0
0
0
17
% H
% Ile:
0
9
0
25
0
0
17
17
9
17
9
25
0
0
0
% I
% Lys:
9
0
9
0
0
0
0
0
25
0
17
0
0
0
9
% K
% Leu:
9
0
0
9
50
17
50
9
0
9
9
0
9
9
9
% L
% Met:
0
0
9
25
9
0
0
9
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
17
0
0
17
9
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
34
9
0
0
9
0
0
0
0
0
9
17
0
% Q
% Arg:
0
9
0
9
0
9
0
9
0
9
9
0
9
0
9
% R
% Ser:
0
0
0
0
9
0
0
25
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
17
9
0
% T
% Val:
17
17
9
0
17
9
0
0
0
25
0
0
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
0
0
0
0
25
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _