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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5B All Species: 10.61
Human Site: S669 Identified Species: 21.21
UniProt: P32019 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32019 NP_005531.2 993 112852 S669 M E N A N I P S V S L S K R E
Chimpanzee Pan troglodytes XP_513330 1149 128671 S825 M E N A N I P S V S L S K R E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_549244 894 103439 I591 L Q K E K F Q I S N N G Q V P
Cat Felis silvestris
Mouse Mus musculus Q8CHC4 1574 172599 S899 P D G T V L V S I K S S A Q E
Rat Rattus norvegicus Q62910 1574 172862 S899 P D G T V L V S I K S S A Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517168 864 99967 F561 N G Q V P C H F S F I P K L N
Chicken Gallus gallus XP_417756 748 85320 T445 Q L Q V E K F T I L N G Q V P
Frog Xenopus laevis Q6P4S2 1019 115278 S712 G V T S Q F V S K N N P G D S
Zebra Danio Brachydanio rerio Q2I6J1 1266 140353 L807 L Q D Q H L L L T V K S L D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569962 850 97512 K547 L P V D F S F K E K D I H A I
Honey Bee Apis mellifera XP_396184 846 96645 L543 L E P S S K E L I I A N T G Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797066 1060 119256 Q722 Q E N E A L P Q V T L G R N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70 N.A. 44 N.A. 21.7 22.2 N.A. 43.9 58.3 20 20.5 N.A. 28.2 38.5 N.A. 36.1
Protein Similarity: 100 74.5 N.A. 62 N.A. 36.8 37 N.A. 61 65.4 36 36.5 N.A. 47.1 55.6 N.A. 52.8
P-Site Identity: 100 100 N.A. 0 N.A. 20 20 N.A. 6.6 0 6.6 6.6 N.A. 0 6.6 N.A. 40
P-Site Similarity: 100 100 N.A. 26.6 N.A. 46.6 46.6 N.A. 13.3 20 20 40 N.A. 6.6 46.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 9 0 0 0 0 0 9 0 17 9 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 9 9 0 0 0 0 0 0 9 0 0 17 0 % D
% Glu: 0 34 0 17 9 0 9 0 9 0 0 0 0 0 42 % E
% Phe: 0 0 0 0 9 17 17 9 0 9 0 0 0 0 0 % F
% Gly: 9 9 17 0 0 0 0 0 0 0 0 25 9 9 9 % G
% His: 0 0 0 0 9 0 9 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 17 0 9 34 9 9 9 0 0 9 % I
% Lys: 0 0 9 0 9 17 0 9 9 25 9 0 25 0 0 % K
% Leu: 34 9 0 0 0 34 9 17 0 9 25 0 9 9 0 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 25 0 17 0 0 0 0 17 25 9 0 9 9 % N
% Pro: 17 9 9 0 9 0 25 0 0 0 0 17 0 0 17 % P
% Gln: 17 17 17 9 9 0 9 9 0 0 0 0 17 17 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 17 0 % R
% Ser: 0 0 0 17 9 9 0 42 17 17 17 42 0 0 9 % S
% Thr: 0 0 9 17 0 0 0 9 9 9 0 0 9 0 0 % T
% Val: 0 9 9 17 17 0 25 0 25 9 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _