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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5B All Species: 1.21
Human Site: Y41 Identified Species: 2.42
UniProt: P32019 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32019 NP_005531.2 993 112852 Y41 R L L G L V R Y R L E H G G Q
Chimpanzee Pan troglodytes XP_513330 1149 128671 K88 G D C F K G Q K A V A M C P E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_549244 894 103439
Cat Felis silvestris
Mouse Mus musculus Q8CHC4 1574 172599 D72 V L R L N L G D T M L H Y L V
Rat Rattus norvegicus Q62910 1574 172862 D72 V L R L N L G D T M L H Y L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517168 864 99967
Chicken Gallus gallus XP_417756 748 85320
Frog Xenopus laevis Q6P4S2 1019 115278 E60 Y R I L Q N A E H Q L S V Q A
Zebra Danio Brachydanio rerio Q2I6J1 1266 140353 L95 T L P E L I Q L Y L Q P S Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569962 850 97512
Honey Bee Apis mellifera XP_396184 846 96645
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797066 1060 119256 S44 R P D I I K Q S S D L T L V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70 N.A. 44 N.A. 21.7 22.2 N.A. 43.9 58.3 20 20.5 N.A. 28.2 38.5 N.A. 36.1
Protein Similarity: 100 74.5 N.A. 62 N.A. 36.8 37 N.A. 61 65.4 36 36.5 N.A. 47.1 55.6 N.A. 52.8
P-Site Identity: 100 0 N.A. 0 N.A. 13.3 13.3 N.A. 0 0 0 20 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 20 N.A. 0 N.A. 26.6 26.6 N.A. 0 0 6.6 40 N.A. 0 0 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 9 0 9 0 0 0 9 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 9 9 0 0 0 0 17 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 9 0 0 9 0 0 0 9 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 0 9 17 0 0 0 0 0 9 9 9 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 25 0 0 0 % H
% Ile: 0 0 9 9 9 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 9 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 34 9 25 17 17 0 9 0 17 34 0 9 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 17 0 9 0 0 0 % M
% Asn: 0 0 0 0 17 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 9 0 0 0 0 0 0 0 0 9 0 9 0 % P
% Gln: 0 0 0 0 9 0 25 0 0 9 9 0 0 17 9 % Q
% Arg: 17 9 17 0 0 0 9 0 9 0 0 0 0 0 9 % R
% Ser: 0 0 0 0 0 0 0 9 9 0 0 9 9 0 0 % S
% Thr: 9 0 0 0 0 0 0 0 17 0 0 9 0 0 0 % T
% Val: 17 0 0 0 0 9 0 0 0 9 0 0 9 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 9 9 0 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _