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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5B
All Species:
8.79
Human Site:
Y839
Identified Species:
17.58
UniProt:
P32019
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32019
NP_005531.2
993
112852
Y839
E
L
W
M
M
V
D
Y
L
Y
R
N
A
V
Q
Chimpanzee
Pan troglodytes
XP_513330
1149
128671
Y995
E
L
W
M
L
V
D
Y
L
Y
R
N
A
V
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549244
894
103439
T752
H
Q
E
D
L
F
Q
T
P
G
M
Q
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHC4
1574
172599
P1102
D
S
S
Q
T
L
E
P
K
R
P
P
P
P
R
Rat
Rattus norvegicus
Q62910
1574
172862
A1266
D
P
L
V
P
I
A
A
P
M
P
P
S
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517168
864
99967
P722
Q
E
D
L
F
Q
T
P
G
M
Q
E
E
L
Q
Chicken
Gallus gallus
XP_417756
748
85320
P606
Q
E
D
L
F
Q
Q
P
G
L
R
S
E
F
E
Frog
Xenopus laevis
Q6P4S2
1019
115278
Q876
D
E
T
V
A
Q
K
Q
L
K
H
P
Y
S
Q
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
P1038
E
D
D
G
N
I
G
P
H
T
G
S
L
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569962
850
97512
W708
V
R
D
W
L
D
T
W
S
D
D
P
F
P
A
Honey Bee
Apis mellifera
XP_396184
846
96645
E704
E
T
P
G
L
P
S
E
I
I
A
I
R
D
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797066
1060
119256
Y893
E
I
W
M
L
V
D
Y
L
F
R
N
G
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
N.A.
44
N.A.
21.7
22.2
N.A.
43.9
58.3
20
20.5
N.A.
28.2
38.5
N.A.
36.1
Protein Similarity:
100
74.5
N.A.
62
N.A.
36.8
37
N.A.
61
65.4
36
36.5
N.A.
47.1
55.6
N.A.
52.8
P-Site Identity:
100
93.3
N.A.
0
N.A.
0
0
N.A.
6.6
6.6
13.3
6.6
N.A.
0
6.6
N.A.
60
P-Site Similarity:
100
100
N.A.
6.6
N.A.
26.6
33.3
N.A.
33.3
33.3
26.6
26.6
N.A.
13.3
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
9
0
0
9
0
17
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
9
34
9
0
9
25
0
0
9
9
0
0
9
0
% D
% Glu:
42
25
9
0
0
0
9
9
0
0
0
9
25
9
9
% E
% Phe:
0
0
0
0
17
9
0
0
0
9
0
0
9
9
0
% F
% Gly:
0
0
0
17
0
0
9
0
17
9
9
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% H
% Ile:
0
9
0
0
0
17
0
0
9
9
0
9
0
17
0
% I
% Lys:
0
0
0
0
0
0
9
0
9
9
0
0
0
0
0
% K
% Leu:
0
17
9
17
42
9
0
0
34
9
0
0
9
9
9
% L
% Met:
0
0
0
25
9
0
0
0
0
17
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
25
0
9
0
% N
% Pro:
0
9
9
0
9
9
0
34
17
0
17
34
9
17
9
% P
% Gln:
17
9
0
9
0
25
17
9
0
0
9
9
0
0
34
% Q
% Arg:
0
9
0
0
0
0
0
0
0
9
34
0
9
0
17
% R
% Ser:
0
9
9
0
0
0
9
0
9
0
0
17
9
9
0
% S
% Thr:
0
9
9
0
9
0
17
9
0
9
0
0
0
0
0
% T
% Val:
9
0
0
17
0
25
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
25
9
0
0
0
9
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
25
0
17
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _