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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCKAR
All Species:
20.91
Human Site:
S259
Identified Species:
46
UniProt:
P32238
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P32238
NP_000721.1
428
47841
S259
E
R
K
P
S
T
T
S
S
G
K
Y
E
D
S
Chimpanzee
Pan troglodytes
XP_526545
428
47894
S259
E
R
K
P
S
T
T
S
S
G
K
Y
E
D
S
Rhesus Macaque
Macaca mulatta
XP_001084186
428
47805
S259
E
R
K
P
S
T
T
S
S
G
K
Y
E
D
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08786
436
48418
S266
G
G
G
G
G
G
S
S
S
S
R
Y
E
D
S
Rat
Rattus norvegicus
P30551
444
49639
S274
E
K
K
P
S
T
G
S
S
T
R
Y
E
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514193
322
36434
V178
R
K
V
N
L
H
P
V
P
S
G
D
G
S
S
Chicken
Gallus gallus
NP_001074970
429
48512
S261
R
E
R
K
G
S
T
S
I
A
K
Y
E
D
G
Frog
Xenopus laevis
P70031
453
51139
T286
A
H
K
N
G
V
S
T
P
T
T
I
P
S
G
Zebra Danio
Brachydanio rerio
XP_697493
446
49641
S264
E
K
E
Y
G
T
S
S
L
K
N
G
D
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P30974
504
58001
V304
S
M
K
S
K
R
K
V
V
R
M
F
I
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782630
517
58443
N341
E
Q
N
G
T
P
L
N
D
L
S
K
K
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
N.A.
N.A.
88.9
88.2
N.A.
48.3
75.5
52
58
N.A.
23.8
N.A.
N.A.
33.2
Protein Similarity:
100
99.5
98.8
N.A.
N.A.
92.8
92.5
N.A.
59.5
85.7
68.2
72.1
N.A.
39.8
N.A.
N.A.
48.1
P-Site Identity:
100
100
100
N.A.
N.A.
40
73.3
N.A.
6.6
40
6.6
20
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
53.3
86.6
N.A.
13.3
53.3
20
46.6
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
10
10
55
10
% D
% Glu:
55
10
10
0
0
0
0
0
0
0
0
0
55
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
10
19
37
10
10
0
0
28
10
10
10
0
19
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
10
% I
% Lys:
0
28
55
10
10
0
10
0
0
10
37
10
10
10
10
% K
% Leu:
0
0
0
0
10
0
10
0
10
10
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
19
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
37
0
10
10
0
19
0
0
0
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
28
10
0
0
10
0
0
0
10
19
0
0
0
0
% R
% Ser:
10
0
0
10
37
10
28
64
46
19
10
0
0
28
55
% S
% Thr:
0
0
0
0
10
46
37
10
0
19
10
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
19
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
55
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _