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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCKBR All Species: 10.61
Human Site: S261 Identified Species: 21.21
UniProt: P32239 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32239 NP_795344.1 447 48419 S261 D S D S D S Q S R V R N Q G G
Chimpanzee Pan troglodytes XP_521813 434 46870 G254 Q S R V R N Q G G L P G A V H
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 L225 V Y S L S S L L I L Y V L P L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P56481 453 49153 S261 D N D S E T Q S R V R N Q G G
Rat Rattus norvegicus P30553 452 48938 S261 E N D S E T Q S R A R N Q G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514193 322 36434 K166 R D G C Y L Q K T K K R R K V
Chicken Gallus gallus Q9DDN6 385 43491 L229 I Y S V S M L L I Q Y V L P L
Frog Xenopus laevis P70031 453 51139 A279 D L N K E A K A H K N G V S T
Zebra Danio Brachydanio rerio XP_002663361 534 59226 G359 E Q K K G Q C G M K N G I S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P30974 504 58001 S297 N T D R Q M E S M K S K R K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022844 471 53720 I274 H R K S D T S I C L E N P S L
Sea Urchin Strong. purpuratus XP_782630 517 58443 E334 Q N T K R E K E Q N G T P L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 22.6 N.A. N.A. 88.3 87.8 N.A. 35.3 23.4 53.4 45.3 N.A. 21.6 N.A. 29.5 32.6
Protein Similarity: 100 91.5 41.1 N.A. N.A. 92.2 92 N.A. 47.8 43.4 71 62.9 N.A. 37.7 N.A. 47.9 51.4
P-Site Identity: 100 13.3 6.6 N.A. N.A. 80 66.6 N.A. 6.6 0 6.6 0 N.A. 13.3 N.A. 20 0
P-Site Similarity: 100 26.6 13.3 N.A. N.A. 100 93.3 N.A. 20 0 40 6.6 N.A. 40 N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 0 9 0 0 9 0 9 % A
% Cys: 0 0 0 9 0 0 9 0 9 0 0 0 0 0 0 % C
% Asp: 25 9 34 0 17 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 0 0 0 25 9 9 9 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 9 0 0 17 9 0 9 25 0 25 25 % G
% His: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % H
% Ile: 9 0 0 0 0 0 0 9 17 0 0 0 9 0 0 % I
% Lys: 0 0 17 25 0 0 17 9 0 34 9 9 0 17 0 % K
% Leu: 0 9 0 9 0 9 17 17 0 25 0 0 17 9 25 % L
% Met: 0 0 0 0 0 17 0 0 17 0 0 0 0 0 0 % M
% Asn: 9 25 9 0 0 9 0 0 0 9 17 34 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 0 17 17 0 % P
% Gln: 17 9 0 0 9 9 42 0 9 9 0 0 25 0 0 % Q
% Arg: 9 9 9 9 17 0 0 0 25 0 25 9 17 0 0 % R
% Ser: 0 17 17 34 17 17 9 34 0 0 9 0 0 25 0 % S
% Thr: 0 9 9 0 0 25 0 0 9 0 0 9 0 0 9 % T
% Val: 9 0 0 17 0 0 0 0 0 17 0 17 9 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 9 0 0 0 0 0 17 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _