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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCKBR All Species: 26.06
Human Site: S434 Identified Species: 52.12
UniProt: P32239 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P32239 NP_795344.1 447 48419 S434 T P S I A S L S R L S Y T T I
Chimpanzee Pan troglodytes XP_521813 434 46870 S421 T P S I A S L S R L S Y T T I
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 S369 N L E V R K N S G P N D S F T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P56481 453 49153 S440 T P S I A S L S R L S Y T T I
Rat Rattus norvegicus P30553 452 48938 S439 T P S I A S L S R L S Y T T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514193 322 36434 G310 T G G S L S R G S Y S H V S I
Chicken Gallus gallus Q9DDN6 385 43491 Q373 K L E A K K S Q F P G D S F T
Frog Xenopus laevis P70031 453 51139 S440 A A T G A S L S K F S Y T T V
Zebra Danio Brachydanio rerio XP_002663361 534 59226 S521 T A T G A S M S K F N Y T T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P30974 504 58001 S467 R P A D G S S S P L C L S I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022844 471 53720 T448 T A E L I T L T K E S R D K L
Sea Urchin Strong. purpuratus XP_782630 517 58443 H504 N H P V Q R P H S T N Y T N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 22.6 N.A. N.A. 88.3 87.8 N.A. 35.3 23.4 53.4 45.3 N.A. 21.6 N.A. 29.5 32.6
Protein Similarity: 100 91.5 41.1 N.A. N.A. 92.2 92 N.A. 47.8 43.4 71 62.9 N.A. 37.7 N.A. 47.9 51.4
P-Site Identity: 100 100 6.6 N.A. N.A. 100 100 N.A. 26.6 0 53.3 46.6 N.A. 26.6 N.A. 20 13.3
P-Site Similarity: 100 100 26.6 N.A. N.A. 100 100 N.A. 40 6.6 73.3 80 N.A. 40 N.A. 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 9 9 50 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 17 9 0 0 % D
% Glu: 0 0 25 0 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 17 0 0 0 17 0 % F
% Gly: 0 9 9 17 9 0 0 9 9 0 9 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 9 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 34 9 0 0 0 0 0 0 0 0 9 42 % I
% Lys: 9 0 0 0 9 17 0 0 25 0 0 0 0 9 0 % K
% Leu: 0 17 0 9 9 0 50 0 0 42 0 9 0 0 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 0 0 9 0 0 0 25 0 0 9 9 % N
% Pro: 0 42 9 0 0 0 9 0 9 17 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 9 9 9 0 34 0 0 9 0 0 0 % R
% Ser: 0 0 34 9 0 67 17 67 17 0 59 0 25 9 0 % S
% Thr: 59 0 17 0 0 9 0 9 0 9 0 0 59 50 17 % T
% Val: 0 0 0 17 0 0 0 0 0 0 0 0 9 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 59 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _